Search

for
Search:

Did you mean Janus Kinase 1 Inhibitor?

GlossaryJAK inhibitor (Janus Kinase 1 Inhibitor)

blocks enzymes involved in immune response and inflammation

A JAK inhibitor, also known as a Janus kinase inhibitor or JAKi, is a type of medication that blocks the activity of Janus kinase enzymes. These enzymes play a crucial role in the signaling pathways that regulate immune responses and inflammation. By inhibiting these enzymes, JAK inhibitors can help manage autoimmune diseases and conditions like alopecia areata, where the immune system mistakenly attacks hair follicles.

Related Terms

Learn

3 / 3 results

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

Research

5 / 1000+ results

$Case Report: Reversal of Long-Standing Refractory Diffuse Non-Scarring Alopecia Due to Systemic Lupus Erythematosus Following Treatment With Tofacitinib$

research Case Report: Reversal of Long-Standing Refractory Diffuse Non-Scarring Alopecia Due to Systemic Lupus Erythematosus Following Treatment With Tofacitinib

6 citations, April 2021 in “Frontiers in Immunology”

A patient with lupus and long-term hair loss saw significant hair regrowth after using the drug tofacitinib.

research Treatment of Crohn's Disease and Concomitant Alopecia Areata With Tofacitinib

2 citations, November 2021 in “ACG Case Reports Journal”

Tofacitinib successfully treated hair loss in a Crohn's disease patient who previously used adalimumab.

research Tofacitinib for the Treatment of Severe Alopecia Areata and Variants: A Retrospective Cohort Study of 90 Patients

June 2017 in “Journal of the American Academy of Dermatology”

Tofacitinib is effective and safe for treating severe alopecia areata and related conditions.

research Autophagy Stimulation Improves Erythroid Proliferative Capacity in Models of SF3B1 Mutant MDS

April 2017 in “Leukemia research”

Tofacitinib helped most teenagers in the study regrow hair with mild side effects.

research The Experts Meetings on Psoriasis: Recommendations for Daily Practice

February 2011 in “Annales de dermatologie et de vénéréologie”

Tofacitinib shows promise for treating severe alopecia areata with good safety and effectiveness.

View more "janus kinase 1 3 inhibitor" in research →

Community Join

3 / 3 results

community What else is good. Besides the big 3.

in Chat 34 upvotes 2 months ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community 8 months apart on the mother of all stacks

in Progress Pictures 149 upvotes 1 year ago

User Tricky9555 tried various hair loss treatments for 8 months with no visible results. Others suggested considering a hair transplant, checking thyroid levels, and being patient for up to 24 months for potential results.

community Is it ok to take Xeljanz (A jak inhibitor) while taking finasteride?

in Finasteride 2 upvotes 7 years ago

The conversation is about whether it is safe to take Xeljanz, a JAK inhibitor, while also taking finasteride for hair loss. The concern is that Xeljanz weakens the immune system, which could be risky.