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    Glossary JAK3 Inhibitor

    blocks an enzyme involved in immune response and inflammation

    A JAK3 Inhibitor, also known as a Janus Kinase 3 Inhibitor, is a type of medication that blocks the activity of the JAK3 enzyme. This enzyme is involved in the signaling pathways that regulate immune responses and inflammation. By inhibiting JAK3, these drugs can help treat autoimmune diseases and conditions like alopecia areata, where the immune system mistakenly attacks hair follicles.

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    Research 10 of 534

    1. Emerging Topical and Systemic JAK Inhibitors in Dermatology Frontiers in Immunology · 2019 · 277 citations
    2. Janus kinase (JAK) inhibitors for the treatment of skin and hair disorders: a review of literature Journal of Dermatological Treatment · 2016 · 40 citations
    3. Hair Growth Effect of Emulsion Extracted Brevilin A, a JAK3 Inhibitor, from Centipeda minima Processes · 2020 · 15 citations
    4. Under Development JAK Inhibitors for Dermatologic Diseases Mediterranean Journal of Rheumatology · 2020 · 14 citations
    5. Unraveling Ritlecitinib: an in-depth analysis of JAK3 inhibitor for the treatment of alopecia areata Expert Opinion on Drug Metabolism & Toxicology · 2024 · 2 citations
    6. Discovery of a novel and highly selective JAK3 inhibitor as a potent hair growth promoter Journal of translational medicine · 2024
    7. 153 Effectiveness of OR-101, a next generation highly selective JAK3 inhibitor, in a humanized murine model of alopecia areata 2023
    8. Which is the ideal JAK inhibitor for alopecia areata – Baricitinib, tofacitinib, ritlecitinib or ifidancitinib - Revisiting the immunomechanisms of the JAK pathway Indian Dermatology Online Journal · 2023
    9. Evaluating Current and Emergent JAK Inhibitors for Alopecia Areata: A Narrative Review Dermatology and Therapy · 2025
    10. JAK inhibitors in dermatology: The promise of a new drug class Journal of the American Academy of Dermatology · 2017 · 355 citations
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