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    GlossaryJanus Kinase 3

    enzyme involved in immune cell signaling pathways

    Janus Kinase 3 (JAK3) is an enzyme that plays a crucial role in the signaling pathways of certain types of immune cells. It is involved in the transmission of signals from various cytokine receptors, which are important for the development and function of the immune system. Mutations or malfunctions in JAK3 can lead to immune disorders and have been targeted in treatments for conditions like alopecia areata and rheumatoid arthritis.

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      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

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      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

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