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    Glossary Brepocitinib

    medication that inhibits enzymes involved in inflammation

    Brepocitinib is a medication that inhibits certain enzymes known as Janus kinases (JAKs) and tyrosine kinase 2 (TYK2). These enzymes play a role in the inflammatory process, and by blocking them, Brepocitinib can help reduce inflammation and is being studied for the treatment of autoimmune conditions like alopecia areata, psoriasis, and other inflammatory diseases.

    Research 10 of 140

    1. A phase 2a randomized, placebo-controlled study to evaluate the efficacy and safety of the oral Janus kinase inhibitors ritlecitinib and brepocitinib in alopecia areata: 24-week results Journal of the American Academy of Dermatology · 2021 · 138 citations
    2. Ritlecitinib and brepocitinib demonstrate significant improvement in scalp alopecia areata biomarkers 2021 · 36 citations
    3. Maintenance, withdrawal, and re-treatment with ritlecitinib and brepocitinib in patients with alopecia areata in a single-blind extension of a phase 2a randomized clinical trial Journal of the American Academy of Dermatology · 2021 · 20 citations
    4. A phase 2a trial of brepocitinib for cicatricial alopecia Journal of the American Academy of Dermatology · 2024 · 17 citations
    5. 290 Brepocitinib improves cicatricial alopecia and downregulates key T-helper biomarkers Journal of Investigative Dermatology · 2024
    6. 802 Molecular effect of brepocitinib in hidradenitis suppurativa (HS) Journal of Investigative Dermatology · 2024
    7. Systematic review of newer agents for the management of alopecia areata in adults: Janus kinase inhibitors, biologics and phosphodiesterase‐4 inhibitors 2022 · 12 citations
    8. A review of Janus kinase inhibitor use in scarring alopecia JAAD reviews. · 2025 · 4 citations
    9. Safety of Janus Kinase inhibitors in Patients with Alopecia Areata: A Systematic Review Clinical drug investigation · 2023 · 3 citations
    10. The relative efficacy of monotherapy with Janus kinase inhibitors, dupilumab and apremilast in adults with alopecia areata: Network meta‐analyses of clinical trials Journal of cosmetic dermatology · 2023 · 2 citations
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