Effect of Tribulus Terrestris Extract on Melanocyte-Stimulating Hormone Expression in Mouse Hair Follicles

December 2006

Yang Liu, Jianwei Lu, Jing An, Xuan Jiang

Tribulus terrestris melanocyte-stimulating hormone MSH hair follicles tyrosinase melanocyte proliferation melanin synthesis epidermal migration

TLDR Tribulus terrestris extract significantly increases MSH expression and melanin production in mouse hair follicles.

The study investigated the effect of Tribulus terrestris extract on melanocyte-stimulating hormone (MSH) expression in C57BL/6J mouse hair follicles. Mice treated with the extract showed a 75% positivity rate of MSH expression in hair follicle melanocytes, compared to only 18.75% in the control group, indicating a significant increase (P<0.01). The extract was found to activate tyrosinase activity, promote melanocyte proliferation, melanin synthesis, and the epidermal migration of dormant melanocytes.

View this study on pubmed.ncbi.nlm.nih.gov →

Discuss this study in the Community →

Related Research

9 / 9 results

research Alcohol Extract from Vernonia Anthelmintica Seed Counteracts Stress-Induced Murine Hair Follicle Growth Inhibition

6 citations , December 2019 in “BMC Complementary and Alternative Medicine”

Alcohol extract from Vernonia anthelmintica seeds may help treat stress-related hair loss.

research Hydrogen Peroxide (H2O2) Suppresses Hair Growth Through Downregulation of Beta-Catenin

13 citations , September 2017 in “Journal of Dermatological Science”

Hydrogen peroxide in hair dye can cause hair loss.

Exogenous Stimulation with Eclipta Alba Promotes Hair Matrix Keratinocyte Proliferation and Downregulates TGF-β1 Expression in Nude Mice

research Exogenous Stimulation with Eclipta Alba Promotes Hair Matrix Keratinocyte Proliferation and Downregulates TGF-β1 Expression in Nude Mice

24 citations , December 2014 in “International Journal of Molecular Medicine”

Eclipta alba extract helps increase hair growth and decrease hair loss-related protein in mice.

research Quercetin Stimulates Melanogenesis in Hair Follicle Melanocyte of the Mouse

20 citations , December 2013 in “PubMed”

Quercetin boosts melanin production in mouse hair follicles.

research Promotion Effect of Acankoreoside J, a Lupane-Triterpene in Acanthopanax Koreanum, on Hair Growth

17 citations , August 2012 in “Archives of Pharmacal Research”

Acankoreoside J from Acanthopanax koreanum may help promote hair growth.

research Ferrous Ferric Chloride Stimulates Skin Cell Function and Hair Growth in Mice

7 citations , January 2009 in “Biological & pharmaceutical bulletin”

Ferrous Ferric Chloride may improve skin cell function and increase hair growth in mice.

research Thymosin Beta 4 Increases Hair Growth by Activation of Hair Follicle Stem Cells

98 citations , December 2003 in “The FASEB Journal”

Thymosin β4 promotes hair growth by activating stem cells in hair follicles.

Indications for a Brain-Hair Follicle Axis: Inhibition of Keratinocyte Proliferation and Up-Regulation of Keratinocyte Apoptosis in Telogen Hair Follicles by Stress and Substance P

research Indications for a Brain-Hair Follicle Axis: Inhibition of Keratinocyte Proliferation and Up-Regulation of Keratinocyte Apoptosis in Telogen Hair Follicles by Stress and Substance P

125 citations , September 2001 in “The FASEB Journal”

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

research Structure and Function of Melanocytes: Microscopic Morphology and Cell Biology of Mouse Melanocytes in the Epidermis and Hair Follicle

69 citations , January 1995 in “PubMed”

Mouse melanocyte structure and function are influenced by genetics, hormones, and environmental factors.

Effect of Tribulus Terrestris Extract on Melanocyte-Stimulating Hormone Expression in Mouse Hair Follicles

Related Community Posts Join

community 5 months on Minoxidil and 1 mg Fin every day.

community Is this supplement safe? Can it raise dht?

community Tribulus Terrestris and Zinc to boost libido on fin

community Hair Restoration Log (Weekly 1.5 mm microneedling + QOD 0.5 mg Finasteride + Daily 50 mg 5% RU58841)

community Scientific evidence for Peppermint & Rosemary oils + My Experience

community How many mgs of zinc should I take while taking fin? I want to potentially offset side effects but not ruin the effectiveness of fin. I take .5 mg fin daily