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Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Optimized film improves finasteride skin absorption and treatment efficiency.

Researchers found two enzymes in Avicennia marina that help produce maslinic acid and corosolic acid, which have medicinal benefits.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Finasteride helps hair regrowth in frontal fibrosing alopecia.

A new compound effectively inhibits human 5α-reductase 1.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

Women with female-pattern baldness produce more testosterone, but 5a-reductase inhibition treatment won't help.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.