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Alopecia areata can show unusual red-dotted vessels and dithranol treatment may mask typical patterns.

Lichen planopilaris in men often involves scalp redness and itching, with some also having hair loss, mucosal lichen planus, or thyroid disease, and treatment improved symptoms in nearly half of the cases.

Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.

A 68-year-old woman with lupus and blood disorders improved after increased steroids and immunoglobulin treatment.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

Biodegradable microneedle patches help topical steroids work better for prurigo nodularis.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

No link found between specific genes and female pattern hair loss.

A new compound effectively inhibits human 5α-reductase 1.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Finasteride effectively blocks enzyme causing male pattern baldness.

Four-amino acid part makes enzyme sensitive to finasteride.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Dutasteride is more efficient than finasteride, but individual results vary.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Scientists found new, better-working inhibitors for a hormone-related enzyme.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.