49 citations
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March 2014 in “Journal of Investigative Dermatology” This study demonstrated that combining AMD3100 with low-dose tacrolimus in a stem cell mobilization approach significantly reduced wound healing time and improved scar and hair follicle regeneration in full-thickness skin wounds.
1 citations
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January 2015 In this study, gel containing apigenin and celery herb extract was observed to effectively stimulate hair growth and did not cause skin irritation in male Sprague-Dawley rats.
17 citations
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May 2011 in “Gene Therapy” This study found that transfecting hair follicle stem cells with a PEI-DNA complex expressing hTERT stimulated hair growth in rats by inducing follicle neogenesis and promoting the anagen phase.
In this research presented at the BEYOND Biohacking Conference 2026, a regenerative skincare serum using plant-derived Consortia Factors® showed significant age spot lightening and improvements in skin smoothness, firmness, and radiance over eight weeks in a study with 35 women.
316 citations
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June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that using a standardized protocol with microspheres of approximately 1.5 micrometers enhances penetration into hair follicles, particularly when skin is treated with cyanoacrylate skin surface stripping.
November 2024 in “EMJ Dermatology” In clinical studies, inhibiting androgen receptor expression using CosmeRNA ARI SAMiRNA micelles effectively treated androgenetic alopecia by significantly increasing hair growth, as reported in this research.
2 citations
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September 2023 in “Journal of the American Academy of Dermatology” CTP-543 effectively promotes hair regrowth in adults with moderate to severe alopecia areata.
March 2026 in “Frontiers in Veterinary Science” This study found that all-trans retinoic acid (ATRA) inhibits proliferation and promotes apoptosis in secondary hair follicle-derived dermal papilla cells from cashmere goats, likely via the TGF-β2/Smad2/3 signaling pathway.
August 2024 in “Biomolecules & Therapeutics” In this study, the researchers reported that a newly developed PYGL inhibitor, HTPI, enhanced hair growth in an ex-vivo culture by reducing oxidative damage in hDPCs and inhibiting glycogen degradation in hORSCs, showing potential as a treatment for hair loss comparable to minoxidil.
9 citations
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January 2009 in “Journal of the European Academy of Dermatology and Venereology” This study found that a cream containing 6.0% Stryphnodendron adstringens bark extract effectively reduced terminal hair growth and improved skin conditions in women with excessive terminal hair.
1 citations
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April 2025 in “Drug Delivery and Translational Research”
11 citations
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December 2018 in “Bone” This study found that a high-energy shock wave can increase osteogenic activities in human mesenchymal cells, offering insights into potential therapeutic targets for trauma-induced heterotopic ossification.
56 citations
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July 2014 in “PloS one” This study found that selective androgen receptor modulators (SARMs) significantly inhibited tumor growth and metastasis-promoting factors in AR-positive triple-negative breast cancer models.
72 citations
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October 2009 in “The FASEB journal” This study found that thyrotropin-releasing hormone (TRH) acts as a potent stimulator of hair growth in human scalp hair follicles, promoting elongation and prolonging the anagen phase.
17 citations
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May 2014 in “Cell transplantation” This study demonstrated that genetically engineered stem cells from human hair follicles can reverse hyperglycemia and reduce mortality in mice with type 1 diabetes by overexpressing the human insulin gene.
4 citations
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August 2025 in “Journal of Food Science” This review highlights that Tremella fuciformis polysaccharide exhibits various bioactivities, such as antioxidant and immune-modulating effects, and explores its potential applications in food, pharmaceutical, and cosmetic industries.
91 citations
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August 2019 in “Frontiers in Microbiology” This study found that the RpoN/RpoS pathway regulates gene expression in Borrelia burgdorferi, influencing its ability to persist in mammals and adapt to different hosts.
This article discusses a novel device for applying mediums to human and animal tissues and reports no new clinical results, focusing on its potential for precise applications and enhanced cell transplants.
March 2026 in “Bioengineering & Translational Medicine” This study reported that a modified version of Thymosin beta 4, called PEG-rTβ4, demonstrated potential as a treatment for acute myocardial infarction by improving cardiac function and reducing cell death via specific biochemical pathways, suggesting its promise in drug development efforts.
The study reported that a poly herbal gel containing Lagenaria siceraria, Trichosanthis cucumarina, and Tridax procumbens promoted hair growth in human volunteers, with noticeable effects observed after 90 days.
15 citations
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September 2008 in “Archives of Dermatological Research” In this study, topical 5% roxithromycin was effective in restoring hair growth in about half of individuals with androgenetic alopecia without causing adverse effects.
2 citations
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January 2017 in “Journal of Cosmetics, Dermatological Sciences and Applications” In this study, TrichotechTM, a phytocomplex derived from essential oils, enhanced fibroblast proliferation, increased FGF-7 and FGF-10 gene expression, and boosted collagen content in cultured human fibroblasts.
January 2008 in “Summit (Simon Fraser University)” This article describes viDA Therapeutics Inc.'s focus on developing new drugs for age-related conditions using their proprietary granzyme-based approach but reports no clinical outcomes, primarily discussing their funding and business strategy.
This study found that gels containing glycyrrhizic acid and aqueous Glycyrrhiza glabra extract significantly reduced underarm hair growth in terms of area, thickness, length, and number compared to their gel bases.
April 2019 in “Journal of the Endocrine Society” This study found that in male mouse pancreatic islet β cells, testosterone enhances glucose-stimulated insulin secretion by being locally converted into dihydrotestosterone and estradiol.
156 citations
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December 2012 in “Cell Stem Cell” This review explores the role of TGF-β superfamily pathways in stem cell environments and their implications for tissue regeneration and cancer development, reporting no new experimental results.
In a rodent study, a flexible, self-powered triboelectric nanogenerator wound patch combining electrostimulation and photothermal effects was found to efficiently accelerate wound healing and hair follicle regeneration.
March 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers developed a new method called Enriched-GF, which enhances growth factor recovery from platelet concentrates through a combination of glass bead activation, freeze-thaw cycling, and calcium stimulation, outperforming conventional methods by providing higher and more consistent yields for regenerative medicine applications.
6 citations
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July 2016 in “Doklady Biochemistry and Biophysics” This study found that GD-23, a dipeptide ligand of TSPO, exhibited an anxiolytic effect in the elevated plus maze test, which was inhibited by selective neurosteroid synthesis inhibitors, suggesting a neurosteroidogenic mechanism.