June 2024 in “Skin Research and Technology” In this study, researchers observed significant differences in microbial composition between UV-induced fluorescent and non-fluorescent scalp areas in patients with androgenetic alopecia, noting a higher abundance of Cutibacterium in the fluorescent regions.
May 2024 in “Journal of cosmetic dermatology” This study investigated the effects of heat-treated Limosilactobacillus fermentum LM1020 on hair growth and reported increased hair density, improved cellular activity, and beneficial scalp microbiota changes in patients with androgenetic alopecia over 24 weeks.
April 2024 in “Animal models and experimental medicine” The researchers reported that platelet-rich plasma treatment increased hair growth in androgenic alopecia patients, potentially by altering scalp microbiota composition, including increased Cutibacterium and decreased Staphylococcus and Lawsonella.
February 2024 in “Journal of applied pharmaceutical research” This study formulated herbal hair oils using extracts such as Coconut and Amla, observing significant improvements in hair growth promotion, antioxidant, and antimicrobial properties in animal models, suggesting potential natural remedies for hair care with further research needed for human application.
This study suggests that human hair keratin-based gradient hydrogels incorporating silver ions may serve as promising dermal templates for wound healing, demonstrating favorable mechanical properties, cell interaction, and antibacterial activity.
January 2024 in “Medicinska istrazivanja” This case report describes erosive pustular dermatosis of the scalp in a 55-year-old woman, which improved rapidly with oral antibiotics and topical corticosteroids but resulted in permanent scarring alopecia, emphasizing the need for prompt diagnosis and treatment to minimize scarring.
January 2024 in “International Journal of Pharmaceutical Research and Development” This study explored the development of herbal hair gels using natural extracts like flaxseed and guava leaves, targeting the reduction of dandruff and regulation of hair loss through antimicrobial and anti-inflammatory properties, though specific results of efficacy are not reported.
December 2023 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” In this study, researchers observed that Folliculitis decalvans diagnoses were often delayed, with severe cases linked to hidradenitis suppurativa and Staphylococcus aureus infection, and highlighted the need for better dermatological training to reduce these delays.
November 2023 in “Journal of Investigative Dermatology” Inhibiting EGFR weakens skin's defense against bacteria.
September 2023 in “International Journal of Cosmetic Science” The researchers observed that two non-antimicrobial shampoos caused a significant increase in fungal germs but did not affect the overall scalp microbiota diversity over two weeks, suggesting these formulations may preserve or stimulate the scalp microbiota without adverse effects.
September 2023 in “Clinical, cosmetic and investigational dermatology” In this study, the researchers found that a 28-day topical treatment with a postbiotic ferment complex notably altered the scalp microbiome in women with sensitive scalps, increasing certain bacterial species and decreasing others, while also reportedly alleviating symptoms of sensitive skin syndrome in all participants.
August 2023 in “Veterinary Science and Medicine Journal” In this case study, the researchers diagnosed a young male cat with dermatitis caused by a fungal infection, specifically identifying Penicillium and Aspergillus species, and observed improvement in symptoms following a two-week treatment with grisofulvin, chlorphenamine maleate, and fish oil shampoo.
August 2023 in “International Journal of Molecular Sciences” In this study, researchers developed a new sodium alginate/chitosan/Zn2+ hydrogel that showed improved physical properties, antibacterial activity, and biocompatibility, and demonstrated enhanced wound healing and skin regeneration in an in vitro model.
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study identified key trends and influential contributors in skin microbiome research from the past decade, highlighting the growing publication rates, major players like the USA, and prominent researchers such as Gallo RL.
June 2023 in “Benha Journal of Applied Sciences” In this study, researchers isolated gram-positive bacteria from acne lesions in 50 patients, finding that Staphylococcus epidermidis, Staphylococcus aureus, Micrococcus luteus, and Leuconostoc mesenteroides were present at varying frequencies, indicating multimicrobial causes for acne vulgaris.
April 2023 in “Journal of Investigative Dermatology” This study found that the type 2 cytokines IL-4 and IL-13 may amplify Staphylococcus aureus-induced inflammation and barrier disruption in atopic dermatitis, potentially worsening skin defense against this bacterium.
January 2023 in “Fundamental toxicological sciences” In this study, mozuku-derived ultra-high-molecular-weight fucoidan was found to inhibit the growth of skin bacteria like Staphylococcus aureus but not other tested bacteria such as Cutibacterium acnes.
November 2022 in “Journal of Investigative Dermatology” This study found that sodium butyrate, a metabolite from the HF microbiome, significantly delayed catagen onset and promoted key physiological processes in cultured human hair follicles.
research Skin
August 2022 This review examines the structure and function of the skin in goats and the factors affecting fiber growth, particularly in cashmere and mohair-producing breeds, without presenting new research data.
January 2022 in “Journal of pharmacognosy and phytochemistry” This study found that a polyherbal gel made from guava leaves, amla, and aloe is effective against candidiasis on the skin, with additional benefits of nourishing hair and preventing premature graying.
May 2021 in “British Journal of Dermatology” This review discusses the composition and role of the hair follicle microbiome in health and disease, highlighting that our understanding remains limited and stressing the need for more comprehensive studies.
April 2021 in “Journal of Investigative Dermatology” This study found that CD1a-restricted CD4+ T cells responsive to lysyl-phosphatidylglycerol were more frequent in the blood of atopic dermatitis patients, suggesting a potential role in the disease's Th2-mediated pathology.
March 2021 in “Actas Dermo-Sifiliográficas” This review discusses the scalp microbiome's unique features and its potential role in hair disorders, suggesting that microbiome-targeted treatments could offer new therapeutic options, though no clinical results are reported.
September 2020 in “Journal of Investigative Medicine” This article discusses the role of the microbiome in different forms of alopecia and highlights the importance of Omics approaches for future research, but it provides no new clinical results.
July 2020 in “International journal for research in applied science and engineering technology” This study reports that a newly formulated herbal shampoo using natural ingredients like fenugreek and shikakai was successfully developed to eliminate harmful synthetic components in anti-dandruff shampoos.
January 2020 in “Social Science Research Network” This study found that skin bacteria contribute to regeneration in wound healing and WIHN by promoting IL-1β signaling, challenging the view that sterility is always beneficial for healing small wounds.
May 2019 in “Eurasian Journal of Biosciences” In this study, researchers observed that fenugreek aqueous extract was more effective than its alcohol extract in inhibiting the growth of bacteria associated with acne, particularly gram-positive bacteria like Staphylococcus epidermidis and Staphylococcus aureus.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers reported that DHT may reduce the inflammatory responses induced by C. acnes in androgen-sensitive human sebocyte cells, suggesting a potential link between androgens and infection in sebaceous disorders.
September 2018 in “Practical diabetes” This article reviews various skin conditions and infections associated with diabetes, noting that people with diabetes are at higher risk for skin conditions such as cellulitis, folliculitis, and skin cancer, and reports no new clinical results.
July 2018 in “British Journal of Dermatology” Hair regrowth was seen in 83% of children with alopecia, immune system plays a role in the condition, and various treatments showed effectiveness for hair and nail disorders.