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New targeted immunotherapies are improving treatment for inflammatory skin diseases.

Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

Adding a second method to PROTACs could improve cancer treatment.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

A specific genetic change is linked to mental disorders, intellectual disability, and possibly autoimmune disease in a family.

Non-surgical procedures can help reduce wrinkles and stimulate skin repair by understanding skin aging at the molecular level.

Mesenchymal stem cells could help treat aging-related diseases better than current methods.

The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.

Dermal papilla cells can help regrow hair and are promising for hair loss treatments.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.

Birt–Hogg–Dubé syndrome is a rare genetic condition causing skin lesions, lung cysts, and a higher chance of kidney cancer.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.

The research suggests that autophagy-related genes might play a role in causing alopecia areata.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Hair follicle regeneration may slow tumor growth.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

Controlled light treatment in mouse skin speeds up healing and hair growth.

Umbilical cord blood is a valuable source of stem cells for medical treatments, but its use is less common than other transplants, and there are ethical issues to consider.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.