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research Substantivity and After‐Rinsing Hair Growth Promotion of Cationic Microparticles of Minoxidil
This study observed that including cationic minoxidil particles in a shampoo facilitated notable hair growth promotion despite a negative surface charge after rinsing, likely due to ionic interactions with the skin.
research UV SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS DETERMINATION OF FINASTERIDE AND TAMSULOSIN IN COMBINED DOSAGE FORM
This study developed and validated a UV spectrophotometric method for accurately measuring finasteride and tamsulosin in solutions and tablets, demonstrating good sensitivity and precision.
research Ultrastructural aspect of the keratinolytic activity of piedra.
This article discusses recent findings on piedra infections in hair and their keratinolytic activities, but reports no new clinical results.
research Metabolism of subtoxic levels of selenium in animals and humans.
This study observed that the intestinal absorption of selenium varies depending on its chemical form, with selenomethionine being absorbed efficiently and selenium as selenodiglutathione or selenodicysteine being absorbed faster than selenite.
research RP-HPLC assay method for simultaneous estimation of tamsulosin hydrochloride and finasteride in pharmaceutical dosage form
This study successfully developed and validated a sensitive and precise liquid chromatography method for simultaneously estimating tamsulosine hydrochloride and finasteride in tablets, showing high accuracy and minimal interference from excipients.
research Cytotoxic Evaluation of Hair Relaxers and Straighteners Actives in Human-Derived Skin Cells
This study demonstrated that hair relaxers containing common chemicals significantly reduced cell viability and increased apoptosis in human skin cells, suggesting potential toxicity that could be assessed with advanced in vitro technologies rather than animal testing.
research Effect of Disulfide Bonds in Human Hair Fibers on the Melting Behavior of Their Crystalline Structure
This study investigated the effect of peracetic acid treatment on hair fiber structure and found that disulfide bond oxidation altered thermal properties while preserving the α-crystal structure, suggesting different stabilizing interactions in hair fibers.
research Solid lipid nanoparticles suspension versus commercial solutions for dermal delivery of minoxidil
This study found that solid lipid nanoparticles with minoxidil were as effective as commercial solutions for skin penetration and were non-corrosive, indicating potential for hair loss treatment.
research Photo-Responsive Ascorbic Acid-Modified Ag2S–ZnS Heteronanostructure Dropping pH to Trigger Synergistic Antibacterial and Bohr Effects for Accelerating Infected Wound Healing
This study found that PEGylated Ag₂S-ZnS@TGA-AA heteronanostructures, activated by light exposure, showed synergistic antibacterial effects against multidrug-resistant bacteria, significantly accelerating the healing of MRSA-infected wounds in comparison to untreated wounds.
research Cavitating Osmotic Demyelination Syndrome Following Correction of Chronic Hyponatremia in Sheehan’s Syndrome: A Novel Case Report
Careful management of chronic hyponatremia is crucial to prevent severe neurological issues.
research Finasteride 98319‐26‐7
research Green formulation of spironolactone loaded chitosan coated nano lipid carrier for treatment of acne vulgaris: a randomized double-blind clinical trial
In a double-blind clinical trial, this study found that a gel containing chitosan-coated spironolactone nanoparticles effectively reduced acne lesions over 8 weeks without adverse skin effects, suggesting potential for enhanced acne treatment through targeted skin delivery.
research Mechanism of action of minoxidil sulfate-induced vasodilation: a role for increased K+ permeability.
In this study, minoxidil sulfate was found to relax norepinephrine-induced contractions in rabbit mesenteric arteries, possibly by acting as a K+ channel agonist, but it did not relax K+-induced contractions.
research Determination of Minoxidil by Bleaching the Permanganate Carrier Solution in a Flow-Based Spectrophotometric System
This study demonstrated that a flow injection method using potassium permanganate for detecting minoxidil provided accurate recoveries and agreed closely with HPLC results, showing potential for effective analysis of commercial samples.
research N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase
This study identified N-acyl arylsulfonamides, particularly N-(Boc-piperidine-4-carbonyl)-benzenesulfonamides, as steroid sulfatase inhibitors with improved cellular potency compared to previous compounds.
research Morphological and Macromolecular Structure
research Morphological and Macromolecular Structure
research Compatibility Studies of Minoxidil with Different Excipients by Using DSC, TGA and FTIR
In this study, researchers found that minoxidil is compatible with excipients such as Beta-cyclodextrin and cellulose, while it is incompatible with Eudragit S 100 and mannitol, indicating potential formulation challenges in pharmaceutical applications.
research DEVELOPING AND VALIDATING AN HPLC METHOD TO QUANTIFY SIMULTANEOUSLY DUTASTERIDE AND THEIR RELATED MOLECULES (DUTASTERIDE ACID, 2,5 BIS- (TRI FLUORO METHYL)-ANILINE AND DUTASTERIDE 17 α-EPIMER) IN CAPSULES
This study developed a validated HPLC method for accurately estimating dutasteride and its related compounds in capsules, suitable for routine and stability sample analysis.
research Absorption of Excess Selenium and Sulfur by Plants and Animals
This review discusses the forms of selenium and sulfur in soil, their plant absorption, and risks of toxicity to livestock, emphasizing selenium's role in selenosis and sulfur's link to polioencephalomalacia in ruminants; it reports no new experimental results.
research Methods of keratin extraction from wool and hair and prospects of their application in biomedicine and bioengineering
This review discusses the properties and extraction methods of keratins from natural fibers and highlights their promising applications in fields such as biomedicine, bioengineering, and forensic science, but reports no new experimental results.
research Formulation of Sodium Valproate Nanospanlastics as a Promising Approach for Drug Repurposing in the Treatment of Androgenic Alopecia
This study investigated a new formula called SV-loaded nanospanlastics for topical application to treat androgenic alopecia. It showed similar effectiveness to minoxidil lotion but with fewer adverse effects when used to enhance dermal delivery and efficacy of sodium valproate.
research MoS2 Nanoclusters-based biomaterials for disease- impaired wound therapy
This study found that SA-MS hydrogel released Mo4+ ions which promoted healing of disease-impaired wounds by enhancing cell proliferation and angiogenesis, and through its photothermal effects addressed skin cancer-impaired wounds in mice.
research Antibacterial Potency of an Active Compound from Sansevieria trifasciata Prain: An Integrated In Vitro and In Silico Study
This study found that components derived from Sansevieria trifasciata demonstrated notable antibacterial activity against Escherichia coli and Streptococcus aureus, highlighting potential for developing new antibacterial agents.
research Hyaluronate - Minoxidil Conjugates for Transdermal Treatment of Hair Loss
research Dissolving microneedle array patches containing mesoporous silica nanoparticles of different pore sizes as a tunable sustained release platform
In this study, researchers developed a new method for producing dissolving microneedle array patches containing mesoporous silica nanoparticles, successfully confirming nanoparticle deposition and release in both ex vivo and in vivo models.
research Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)
This study synthesized and verified the structures of Setipiprant's major and minor metabolites, confirming their regio- and enantioselectivity from earlier proposals in a clinical study.
research An Overview of Chitosan-Based Composites Containing Silver or Zinc Oxide Nanoparticles: Antimicrobial and Antibacterial Properties, and Biomedical Perspectives
This study reviewed chitosan composites, specifically those with silver or zinc oxide nanoparticles, highlighting their enhanced antimicrobial efficacy and potential biomedical applications despite pure chitosan's limitations such as pH sensitivity and poor solubility.
research Experimental Investigations on Hair Fibers as Diffusion Bridges and Opiates as Solutes in Solution
This in vitro study found that opiate diffusion was more pronounced in damaged hair fibers than in undamaged ones, with high opiate concentrations detected in fiber centerpieces.