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This study explored the solubility and crystal structure of GI197111X, a 5-alpha reductase inhibitor for androgenetic alopecia, finding its solubility in Capmul MCM suitable for a soft gel dosage form.

In this study, Bacillus subtilis strain ALC_02 was observed to enhance phosphorus acquisition in phosphorus-limited dwarf tomato plants by promoting root and root hair growth, with potential implications for developing effective bacterial P biofertilizers.

This study found that using nanoporous silica entrapped lipid-drug complexes enhanced the solubility and bioavailability of dutasteride in beagle dogs.

This study found that a bacterial endophyte from Zea nicaraguensis effectively targets and colonizes plant root hair cells, promoting growth and solubilizing insoluble phosphorus for nutrient uptake.

This study found that type II keratins in proliferating epithelial tissues are phosphorylated at a conserved motif during mitosis and stress, impacting keratin solubilization and reorganization.

This study found that both everyday physical and environmental stresses, as well as chemical treatments, contributed to hair damage, with cuticle layers being more noticeably affected.

This study formulated a minoxidil nanoemulgel with improved solubilization and skin penetration, demonstrating a high entrapment efficiency and sustained drug release in vitro, which suggests potential improvements in treating androgenetic alopecia compared to conventional formulations.

This study investigated multiple alkaline oxidative dehairing systems and found a consistent reaction mechanism for disulfide cleavage across systems, enhancing hair solubilization by enabling structural swelling and water uptake.

In this study, researchers investigated how rhizosphere microorganisms, including specific bacteria and fungi, can regulate plant root architecture in acidic red soils by mechanisms such as hormone production and phosphorus solubilization, potentially enhancing soil productivity.

This study found that anionic HSES achieved high complexation efficiencies with various steroids, significantly enhancing their solubility, while specific β-cyclodextrin thioethers showed selective binding to testosterone and estradiol.

This study found that CMAD wool keratin may protect human hair from damage during repeated bleaching and permanent waving treatments.

This study found that intermediate filaments and matrix proteins in presumptive hair shaft cells are synthesized sequentially, identifying a new polypeptide component that changes during hair cell differentiation.

Nano-liposol with astaxanthin may improve antioxidant and wound healing effects.

This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.

This review highlights that transferosomes, or ultradeformable lipids, show promise for improving dermal delivery, exhibiting efficient drug transport across the skin's barrier and offering potential benefits for treating chronic skin disorders with better bioavailability.

The researchers reported that sterol surfactants with a bulky planar structure effectively solubilized ultraviolet ray absorbers, offering a stable solution more efficiently than other surfactants.

This review explores the formulation, characterization, and applications of microemulsions, highlighting their potential for enhanced cutaneous drug delivery by improving bioavailability and enabling sustained release of both hydrophilic and hydrophobic drugs.

This article reviews strategies like microemulsions to improve adapalene delivery in acne treatment but reports no new clinical results.

This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.

In this study, carboxymethylalanyl disulfide keratin was shown to effectively prevent hair damage during repeated bleaching and permanent waving treatments.

This article reviews methods for dissolving hair proteins and describes how solvents and molecules with hydrophobic groups interact with hair; it presents no new research findings.

This study found that about 80% of known fullerene-binding proteins rank in the top 10% of scorers for C60 docking sites, confirming the accuracy of the predictive model used.

This study used proteomics to identify various proteins in human hair, which may help develop novel biomarkers for hair health, disease, and aging.

This study proposes a new method to selectively isolate keratin-associated proteins and keratin from human hair, suggesting that KAPs may support keratin fibers in hair structure.

This study found that liquid crystalline nanoparticles formulated with Cremophor surfactants significantly enhanced skin permeation of finasteride compared to lower surfactant concentrations.

This study found that nanoemulsions incorporating skin penetration enhancers significantly increased the permeation of minoxidil through human skin compared to aqueous control solutions.

This study suggests that true binary and ternary inclusion complexes were formed between finasteride and 2-hydroxypropyl-ß-cyclodextrin, with or without the addition of specific polymers.

This study found that freeze-dried finasteride nanoparticles improved the stability, solubility, and in vitro dissolution of the drug, indicating potential benefits for poorly water-soluble drugs.

This article describes the synthesis of novel polyamine-modified minoxidil analogs and conjugates to potentially enhance minoxidil's biological activity, selectivity, and water solubility, but reports no new biological results.