56 citations
,
March 2016 in “International Wound Journal” This review concludes that autologous split-thickness skin grafting remains the gold standard for safety and efficacy in treating chronic leg ulcers, with greater success in venous ulcers.
45 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This article reviews factors affecting follicular unit extraction, emphasizing the need to tailor procedures to individual patient characteristics, but reports no new experimental findings.
44 citations
,
July 2020 in “Stem Cell Research & Therapy” This review discusses recent advancements in the study and application of epidermal stem cells for wound healing and tissue engineering, without presenting new experimental findings.
43 citations
,
July 2019 in “Stem Cells International” This review discusses advances and challenges in skin tissue engineering, focusing on developing 3D constructs for functional skin substitutes, and reports no new clinical results.
39 citations
,
March 2009 in “Clinics in plastic surgery” This review discusses the evolution and studies of injection lipolysis for fat reduction, highlighting the need for more research to ensure patient safety and treatment efficacy; it reports no new clinical results.
38 citations
,
December 2012 in “Journal of Cutaneous Pathology” This review discusses the significance of elastic tissue staining in dermatopathology, particularly for diagnosing primary elastic tissue disorders and other skin conditions, but reports no new clinical results.
34 citations
,
May 2021 in “Journal of Nanobiotechnology” This study found that electrospun short fibrous sponges effectively mimic the 3D extracellular matrix, promoting tissue regeneration, angiogenesis, and wound healing in diabetic rats better than 2D fiber membranes.
31 citations
,
October 2021 in “Antibiotics” This study observed that post-surgical use of chlorhexidine digluconate mouth rinse in patients may induce a fibrotic transformation in gingival tissue, promoting a scar-like wound healing response.
29 citations
,
December 2021 in “Pharmaceutics” This review discusses the use of phospholipid soft vesicle carriers to improve the delivery and therapeutic outcomes of topical treatments for various skin conditions, but reports no new clinical results.
29 citations
,
December 2012 in “Fibrogenesis & Tissue Repair” This review discusses the roles of tissue-specific and mesenchymal stromal cells in tissue repair and reparative disorders, highlighting potential therapeutic targets for muscle, heart, and lung tissues.
22 citations
,
March 2021 in “Materials Today Bio” This review discusses recent advances in developmental tissue engineering for regenerating ectodermal appendages like teeth and glands, emphasizing biomaterial selection and cell culture strategies, but reports no new experimental results.
21 citations
,
July 2020 in “Stem Cell Research & Therapy” This study found that adipose-derived mesenchymal stem cells from type 2 diabetes mice were slightly less effective, yet had comparable therapeutic effects on wound healing compared to non-diabetic controls.
20 citations
,
October 2018 in “Aesthetic Plastic Surgery” This review discusses the potential mechanisms of platelet-rich plasma in facial rejuvenation and reports no new clinical results, indicating a theoretical basis for its use in tissue regeneration.
12 citations
,
March 2018 in “Bioengineering” This review discusses the use of non-transfusional hemocomponents in surgical procedures for tissue regeneration and reports no new empirical findings.
12 citations
,
January 2013 in “IOSR Journal of Agriculture and Veterinary Science” In this study, homogenous platelet rich plasma gel improved wound healing in goats, showing organized collagen and new hair growth within 15 days without inflammation.
11 citations
,
September 2013 in “Otolaryngologic Clinics of North America” This review outlines various techniques to improve facial scars following trauma but reports no new clinical results, highlighting the need for further research to address psychosocial impacts.
10 citations
,
July 2011 in “Wound Repair and Regeneration” This article proposes several potential approaches for scar prevention and therapy, including anti-transforming growth factor-β strategies and tissue-engineered skin, but reports no new clinical results.
10 citations
,
April 2007 in “Aesthetic Plastic Surgery” This study demonstrated the feasibility of a new patient-controlled method for tissue expansion that achieved full expansion in about 3 weeks with minimal complications after mastectomy.
9 citations
,
March 2023 in “Biomimetics” This review discusses current strategies and materials in tissue engineering for skin regeneration, emphasizing design approaches and suggesting directions for future research; it reports no new clinical findings.
9 citations
,
December 2021 in “Journal of Cellular and Molecular Medicine” In this study, researchers found that human adipose tissue-derived mesenchymal stromal cells exhibit significant phagocytic ability against various particles and pathogens, which might enhance strategies for addressing specific local and systemic infections due to their regenerative properties.
9 citations
,
November 2008 in “Facial Plastic Surgery” This article reviews techniques for repairing scalp deformities and concludes that combining older methods with modern hair restoration allows for satisfactory treatment of large scarred areas.
8 citations
,
March 2009 in “Aesthetic Plastic Surgery” This study found that the "flying-wings" expanded scalp flap technique effectively restored hemiscalp defects in children following burns, achieving pleasing aesthetic results and proper hair growth direction with minimal complications.
6 citations
,
April 2022 in “Cellular and Molecular Life Sciences” This study reports that a new protocol using Angio PRP improved wound healing in mice by enhancing key healing processes and regulating inflammation, suggesting potential for clinical advancements.
6 citations
,
July 2017 in “Clinics in Plastic Surgery” This article reviews the management of head and neck burns across different phases but presents no new clinical results.
3 citations
,
July 2025 in “Current Issues in Molecular Biology” This review discusses how dental pulp stem cells and their derivatives may accelerate skin wound healing by modulating inflammation, promoting angiogenesis, optimizing extracellular matrix structure, and enhancing tissue formation, with implications for translating these findings into therapies for skin and mucosal repair.
2 citations
,
January 2023 in “Eastern Journal Of Medicine” This review discusses the use, efficiency, and preparation methods of autologous platelet concentrates in wound healing and periodontal regeneration, but it reports no new clinical findings.
2 citations
,
December 2022 in “PÄDI Boletín Científico de Ciencias Básicas e Ingenierías del ICBI” This review provides an overview of composite scaffold materials for skin that mimic natural dermal tissue, and highlights their potential in treating chronic wounds like diabetic foot by promoting cellular growth.
2 citations
,
September 2019 in “Dermatologic Surgery” This retrospective study observed that hair grafting in burn and postskin graft scars, which preserve deeper skin layers, had more favorable outcomes than in scars extending to the subcutaneous layer.
1 citations
,
December 2023 in “Vestnik stomatologii i čelustno-licevoj hirurgii” This study examined a case of vascular complication following the use of hyaluronic acid-based fillers in lateral temporal lifting, resulting in livedo reticularis, alopecia, and painful injection area requiring three months of treatment.
This article reviews surgical techniques for addressing scalp defects and highlights hair restoration as a cosmetic improvement strategy, but it reports no new clinical results.