research Medical Therapies
Combination therapies might work better for some vitiligo patients, but results vary.
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90-120 / 1000+ resultsresearch Exploring Differentially Expressed Genes by RNA-Seq in Cashmere Goat Skin During Hair Follicle Development and Cycling
The study found key genes and pathways involved in cashmere goat hair growth stages.
research After Skin Wounding, Noncoding dsRNA Coordinates Prostaglandins and WNT7b to Promote Regeneration
Double stranded RNA helps skin wounds heal by coordinating specific proteins and signaling pathways.
research Mapping Human Skin: One Sequenced Cell at a Time
The article concludes that creating a detailed map of normal human skin at the single-cell level is important.
research Melanocyte Cell States Defined and Visualized in Developing Mouse Skin
Researchers found three types of melanocytes in developing mouse skin, each with different genes and locations.
research Spatio-Temporal Regulation of Gene Expression Defines Subpopulations of Epidermal Stem Cells
Different types of skin stem cells can change and adapt, which is important for developing new treatments.
research Comparative Study on Seasonal Hair Follicle Cycling by Analysis of the Transcriptomes from Cashmere and Milk Goats
Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.
research Traditional Chinese Medicine Shi-Bi-Man Regulates Lactic Acid Metabolism and Drives Hair Follicle Stem Cell Activation to Promote Hair Regeneration
Shi-Bi-Man, a Traditional Chinese Medicine, helps grow hair by boosting lactic acid metabolism and activating hair follicle stem cells.
research Evaluation of the Expression of Genes Associated with Inflammation and Apoptosis in Androgenetic Alopecia by Targeted RNA-Seq
WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.
research Skin Keratins
Keratins are important for skin cell health and their problems can cause diseases.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Skin Transcriptome Profiling of Changthangi Goats Highlights the Relevance of Genes Involved in Pashmina Production
Changthangi goats have specific genes that help produce Pashmina wool.
research Non-Invasive Approaches for the Diagnosis of Autoimmune/Autoinflammatory Skin Diseases: A Focus on Psoriasis and Lupus Erythematosus
Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.
research Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome
Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.
research Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin
Hair follicle development and microbes help regulatory T cells gather in newborn skin.
research Inducing Hair Follicle Neogenesis with Secreted Proteins Enriched in Embryonic Skin
Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
research ROBO4 Deletion Ameliorates PAF-Mediated Skin Inflammation by Regulating the mRNA Translation Efficiency of LPCAT1/LPCAT2 and the Expression of PAF Receptor
Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.
research Genome-Wide Detection and Sequence Conservation Analysis of Long Non-Coding RNA During Hair Follicle Cycle of Yak
Researchers found that certain RNA sequences play a role in yak hair growth and these sequences are somewhat similar to those in cashmere goats.
research Dermis-Hair Follicle Communication: Extracellular Microvesicles Signaling for Hair Regeneration
Tiny particles from skin cells can help activate hair growth.
research Smad7-Induced Beta-Catenin Degradation Alters Epidermal Appendage Development
Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.
research The TFIID Subunit TAF4 Regulates Keratinocyte Proliferation and Has Cell-Autonomous and Non-Cell-Autonomous Tumor Suppressor Activity in Mouse Epidermis
TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
research TCF/Lef1-Mediated Control of Lipid Metabolism Regulates Skin Barrier Function
TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.
research Pmg-1 and Pmg-2 Constitute a Novel Family of KAP Genes Differentially Expressed During Skin and Mammary Gland Development
Pmg-1 and Pmg-2 are new genes important for skin and mammary gland development.
research Expression of Hypothalamic-Pituitary-Thyroid Axis Related Genes in Human Skin
Thyroid-related genes are active in skin cells and may affect autoimmune conditions.
research Role of Fibroblast DPP4 in Wound Healing, Scarring, and Regeneration
DPP4 is important for scarring and skin regeneration, and managing its activity could improve skin healing treatments.
research Receptor Activator of NF-κB Stimulates the Proliferation of Epithelial Cells of the Epidermo-Pilosebaceous Unit
RANK-RANKL signaling is essential for hair growth and skin health.
research Dynamic Morphogen-p63 Chromatin Interactions That Guide Epigenetic Changes and p63 Activity in Surface Ectoderm Commitment
The study found that p63 needs signals from morphogens to help skin cells differentiate properly.
research Single-Cell Transcriptomics Defines Keratinocyte Differentiation in Avian Scutate Scales
The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
research Evidence That Myc Activation Depletes the Epidermal Stem Cell Compartment by Modulating Adhesive Interactions with the Local Microenvironment
Myc activation reduces skin stem cells by affecting cell adhesion.
research Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease
Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.