2 citations,
December 2016 in “Experimental cell research” The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
721 citations,
October 2011 in “Nature” Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
19 citations,
December 2015 in “Journal of Materials Chemistry B” Scientists have created a method to deliver specific cells that can regenerate hair follicles, potentially offering a new treatment for hair loss.
57 citations,
March 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
October 2024 in “Biology” Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
5 citations,
July 2018 in “Experimental Dermatology” The "Punch Assay" can regenerate hair follicles efficiently in mice and has potential for human hair regeneration.
85 citations,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
24 citations,
January 2016 in “Lasers in Medical Science” Erbium glass laser treatment may help with skin remodeling, reduce inflammation, and improve skin cell maturation.
133 citations,
September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
65 citations,
March 2018 in “Journal of Dermatological Science” Skin problems can be caused or worsened by physical forces and pressure on the skin.
1 citations,
September 2015 in “Elsevier eBooks” SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
3 citations,
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
207 citations,
March 2012 in “Development” Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
62 citations,
April 2009 in “British Journal of Dermatology” Epidermal stem cells could lead to new treatments for skin and hair disorders.
34 citations,
June 2008 in “In vitro cellular & developmental biology. Animal” Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
26 citations,
July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
16 citations,
January 2007 in “Dermatology” Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.
3 citations,
May 2022 in “Oncogene” Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
28 citations,
January 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
26 citations,
July 2016 in “PLOS ONE” Activating β-catenin in certain skin cells speeds up hair growth in mice.
5 citations,
October 2020 in “Frontiers in Cell and Developmental Biology” Reducing FOXA2 in skin cells lowers their ability to grow hair.
16 citations,
August 2019 in “Cell Proliferation” Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.
13 citations,
November 2013 in “Journal of Endocrinology/Journal of endocrinology” Vitamin D receptor helps control hair growth genes in skin cells.
2 citations,
March 2018 in “Biotechnology Letters” Scientists created a new cell line from Cashmere goat hair and found that cytokeratin 13 is a unique marker for certain skin cells.
6 citations,
February 2013 in “Journal of Visualized Experiments” The method quickly analyzes hair growth genes and shows that blocking Smo in skin cells stops hair growth.
94 citations,
June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
32 citations,
April 2017 in “Scientific Reports” Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.
3 citations,
April 2018 in “Therapeutic Delivery” Hair follicle regeneration and delivery is complex due to many molecular and cellular factors.
32 citations,
July 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.