Consideration When Interpreting Outpatient Data

The document discussed the challenges in interpreting outpatient data, particularly in the context of a study on the percutaneous absorption of potent topical corticosteroids in patients with severe atopic dermatitis. It highlighted that medication weights and self-reporting could overestimate actual usage, suggesting that poor adherence might be a factor. The study found that patients with suppressed serum cortisol levels at discharge had normal levels 41 days post-hospitalization despite continued corticosteroid use. This raised concerns that the actual dose causing HPA axis suppression might be lower than suggested. The document emphasized the need for objective assessment to accurately determine medication application and adherence.