71 citations,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
9 citations,
March 2015 in “International reviews of immunology” Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.
265 citations,
July 2012 in “Cell” The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.
31 citations,
September 2012 in “Journal of biological chemistry/The Journal of biological chemistry” The right amount of retinoic acid is essential for normal hair growth and development.
1 citations,
November 2022 in “Animals” The research found specific genes and pathways that control fur development and color in young American minks.
13 citations,
June 2018 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.
19 citations,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Dermal-epidermal interactions are crucial for hair growth and maintenance.
November 2022 in “Research Square (Research Square)” Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.
3 citations,
April 2022 in “International Journal of Molecular Sciences” Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
61 citations,
October 1996 in “Development” Hair growth can be stimulated by combining certain skin cells, which can rejuvenate old cells and cause them to specialize in hair follicle creation.
31 citations,
September 2013 in “Stem Cells” Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.
72 citations,
July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
60 citations,
March 2011 in “Proceedings of the National Academy of Sciences of the United States of America” RANK-RANKL signaling is essential for hair growth and skin health.
July 2009 in “Medical & surgical dermatology” Low-dose acitretin helps nail psoriasis, stem cells may treat scarring alopecia, Chinese men have lower baldness rates, lateral foldplasty is good for ingrown toenails, hair diameter helps diagnose female baldness, childhood trauma linked to alopecia areata, certain hair-weaving leads to scalp conditions in African American women, and new methods for hair research and understanding hair and sweat gland development were introduced.
5 citations,
September 2015 in “BMC Medical Genetics” The EDAR gene mutation leads to thinner and more deformed hair shafts.
759 citations,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
14 citations,
June 2020 in “BMC genomics” The study identified key genes that regulate the growth cycle of cashmere in goats, which could help improve breeding strategies.
12 citations,
September 2018 in “Naturwissenschaften” Melatonin treatment increases a specific RNA in goat cells that boosts cashmere growth.
10 citations,
September 2022 in “Advanced Healthcare Materials” Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
300 citations,
August 2012 in “Seminars in Cell & Developmental Biology” The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
30 citations,
June 2014 in “Seminars in Immunology” Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.
47 citations,
June 2019 in “Nature Communications” Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
45 citations,
October 2015 in “BMC Genomics” Chicken feather growth involves specific genes and shares similarities with hair development.
29 citations,
December 2016 in “The EMBO Journal” Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
1 citations,
April 2022 in “Regenerative Therapy” Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
3 citations,
August 2023 in “Genes” The document concludes that various signaling pathways and genetic factors are crucial for chicken feather development, affecting poultry quality.
1 citations,
January 2024 in “International journal of molecular sciences” The research identifies genes linked to wool quality in sheep and provides insights to improve wool production.
Thyroid problems can cause hair loss and change hair texture.
2 citations,
March 2023 in “BMC ecology and evolution” Some hair protein genes evolved early and were adapted for use in hair follicles.