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Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Certain genes control the color of human hair by affecting pigment production.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Smart biomaterials that guide tissue repair are key for future medical treatments.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.