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New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Human skin xenografting could improve our understanding of skin development, renewal, and healing.

miR-29a-5p prevents the formation of early hair structures by targeting a gene important for hair growth and is regulated by a complex network involving lncRNA627.1.

New technologies show promise in healing wounds, treating cancer, autoimmune diseases, and genetic disorders.

The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.

ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.

DNA methylation controls lncRNA2919, which negatively affects hair growth.

Modified stem cells that overexpress a specific protein can improve hair growth and reduce hair abnormalities in mice.

Sirtuin 1 could be a potential drug target for treating hypertrophic scars.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

WWP2 is crucial for tooth development in mice.

XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.

Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Blocking certain immune signals can reduce skin damage from radiation therapy.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

Targeting NETs may help reduce fibrosis in Crohn's disease.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

PlncRNA-1 helps hair follicle stem cells grow and develop by controlling a specific cell signaling pathway.

Overexpressing Tβ4 in goats' hair follicles increases cashmere production and hair follicle growth.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.

A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.

Septin4 helps kill colon cancer cells by working with the protein BAX.

Removing p16INK4a from skin cells can lead to faster and more clumped growth, which might help with hair growth.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.