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In this study, researchers developed a multifunctional hydrogel for wound healing, incorporating antibacterial and antioxidant properties that demonstrated significant inflammation reduction and tissue regeneration in animal models, with high antibacterial efficacy against E. coli and S. aureus.

The composite dressing improved wound healing and hair growth in mice.

The hydrogel helps heal wounds without scars by releasing two drugs gradually.

In this study, a newly engineered SFCC hydrogel in animal models demonstrated promising potential for skin reconstruction, promoting hair follicle regeneration, enhancing collagen and cellular proliferation, and accelerating burn healing by supporting favorable immune responses and tissue repair.

This study reports that a silk-based suture with integrated silver nanoparticles and curcumin shows potential for enhanced wound healing and infection prevention, offering multifunctionality and real-time wound monitoring capabilities.

In this animal study, researchers found that nanofibers combining gold nanoparticles with silk fibroin improved wound healing more effectively than silk fibroin alone, promoting faster skin recovery and hair follicle formation in rats over 7 and 21 days.

In this study, a silk fibroin hydrogel containing recombinant NT3 was found to promote scar-less wound healing in a mouse skin injury model by enhancing type III collagen expression and inducing hair follicle formation.

In this study, a novel hydrogel dressing combining photodynamic therapy with organic semiconductor nanoparticles and silk fibroin demonstrated effective antibacterial action and enhanced wound healing and hair follicle regeneration in a mouse model, showing promise as an advanced wound care solution.

This study found that a silk fibroin/sodium alginate scaffold effectively delivers human umbilical mesenchymal stem cells to promote scarless wound healing and hair follicle regeneration in vivo by inducing specific cellular processes and mitigating endoplasmic reticulum stress.

This study found that sericin dressing containing collagen hydrolysate significantly reduced wound healing time and improved scar quality compared to commercial dressing in split-thickness skin graft donor sites.

This study found that an injectable hydrogel, SF-g-SDA, outperformed commercial Tegaderm™ in healing wounds, promoting collagen deposition, and enhancing neovascularization in animal models.

This study found that rabbit hair follicle stem cells, combined with electro-spun nano silk fibers, successfully constructed a tissue-engineered urethra, suggesting potential for future in vivo repair studies.

Animal experiments in this study demonstrated that a new sandwich-like fiber/sponge dressing design, which enhances wound healing through improved moisture management and faster exudate evaporation, resulted in more significant wound size reduction compared to commercial and control dressings.

This review discusses the potential of silk fibroin-based injectable hydrogels as next-generation biomaterials for regenerative medicine, exploring their therapeutic advantages, challenges, and future clinical applications.

This study challenges the idea that tarantulas produce silk from their feet to steady themselves during falls, suggesting instead that the hairs on their feet are chemosensors secreting lymph, not silk.

This study successfully established a transgenic sheep fibroblast cell line expressing the spider dragline silk protein gene, laying groundwork for developing transgenic sheep with this capability in hair follicles.

In vitro, this study found that PTX and HU SF-FA NLCs showed greater cytotoxicity and apoptosis in ovarian cancer cells than pure paclitaxel, suggesting promise as a targeted drug delivery platform.

This study developed a multifunctional TA-MoS2-SF hydrogel for diabetic ulcer treatment, demonstrating enhanced photothermal bactericidal effects, immune environment remodeling, and fibroblast proliferation, suggesting it may serve as an effective 'antibacterial-immunomodulatory-repair' strategy.

In this study, researchers successfully established a stable transgenic sheep fibroblast cell line containing an artificially synthesized spider dragline silk protein gene.

This article describes a surgical technique combining CO2 SilkTouch Laser and Calvitron Hair Transplant System that offers a natural-looking hairline with moderate session length and minimal bleeding, but reports no new clinical outcomes.

This study observed that DNA methylation dynamics, including global hypermethylation and site-specific changes, influenced gene expression associated with immune activation and PI3K-Akt signaling during esophageal tissue regeneration with acellular grafts.

This study involved analyzing hair-removal advertisements and conducting focus group interviews with 28 female university students in Budapest to explore societal attitudes toward female body hair removal, aiming to understand the reasons behind its strong norm compliance.

In this study, MSC-laden silk nanofiber hydrogels accelerated wound healing and enabled scarless skin regeneration with hair follicles, outperforming MSC-free hydrogels in repairing full-thickness skin defects.

In animal models, this study reported that a wound dressing combining quaternized chitin and silk fibroin significantly enhanced vascular reconstruction and hair follicle regeneration, approaching normal tissue levels.

This study suggests that sericin microneedles with antibacterial and directional traction functionalities may enhance infected wound healing by improving skin repair and inhibiting bacterial growth, indicating potential for clinical application.

This study found that using 3D dermal papilla spheroid models enhances extracellular matrix production and hair follicle marker expression, providing insights into hair follicle biology and potential for drug screening.

This review evaluates in vitro hair follicle models, techniques, and challenges without reporting new clinical results, emphasizing their future potential in hair transplantation.