228 citations
,
February 2003 in “Urology” This article discusses the side effects of androgen deprivation therapy for nonmetastatic prostate cancer, highlighting the need for clinical trials to systematically study these effects.
89 citations
,
May 2005 in “Stem Cells” This study found that keratinocyte stem cells in mouse skin are closely related to side population or BCRP1-positive cells based on their localization and marker expression.
80 citations
,
January 1988 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study observed that high-dose spironolactone frequently caused metrorrhagia in women with idiopathic hirsutism, leading the authors to suggest lower starting doses or additional hormonal therapy.
55 citations
,
December 1983 in “Acta Neurologica Scandinavica” This review discusses the side effects of carbamazepine, valproate, and clonazepam, noting that these are rare with long-term use but more common, transient, and generally mild during early treatment.
46 citations
,
December 1997 in “Cancer Nursing” In this study, patients receiving CHOP chemotherapy for aggressive non-Hodgkin's lymphoma reported a wide range of side effects, with all experiencing hair loss by cycle 3 and fatigue as a common issue.
38 citations
,
November 2012 in “Expert Opinion on Drug Safety” This article reviews different acne treatments and emphasizes the importance of being aware of their potential side effects, but reports no new clinical results.
35 citations
,
April 2013 in “Sexual medicine reviews” This review found that 5α-reductase inhibitors are associated with slightly increased rates of sexual dysfunction, gynecomastia, and mood disorders, but the true significance and persistence of these effects remain unclear.
18 citations
,
January 2009 in “Acta neurologica Scandinavica” In this study, the side effects of long-term sodium valproate treatment for refractory epilepsy were generally slight and transient, with severe side effects not observed.
11 citations
,
January 1980 in “PubMed” This article reviews various side effects and concerns related to oral contraceptives, including potential vascular complications and elevated plasma cortisol levels, but reports no new clinical results.
9 citations
,
June 2014 in “Journal of Craniofacial Surgery” The authors concluded that using an expanded temporoparieto-occipital scalp flap for sideburn reconstruction provides satisfactory hair direction and inconspicuous scars in both the donor and recipient areas, with few complications.
7 citations
,
June 2020 in “JAAD Case Reports” This article reviews the development of biocompatible artificial hair for treating hair loss and reports encouraging results from clinical trials, but it provides no new clinical findings.
7 citations
,
January 1989 in “Archives of Dermatological Research” The side gland of Suncus murinus is a good model for studying human sebaceous glands.
6 citations
,
January 2021 in “Journal of The American Academy of Dermatology” This letter discusses adverse events related to low-dose oral minoxidil for alopecia, highlighting age-related risks and stressing the importance of contraindication awareness with no new clinical results presented.
6 citations
,
April 2016 in “PubMed” This review found that dutasteride and finasteride are rarely associated with sexual side effects when used off-label for female hair loss, and suggests further study of their efficacy and side effect profile.
3 citations
,
March 2019 in “Archives of Plastic Surgery” This study found that hair transplantation effectively corrected altered hairlines and scarring arising from midface-lifting surgery, achieving high patient and physician satisfaction scores without adverse events.
3 citations
,
April 2017 in “Zahedan Journal of Research in Medical Sciences” This study observed that nearly all kidney transplant patients experienced complications from immunosuppressive therapy, with excessive hair growth and increased blood sugar being the most common issues.
3 citations
,
April 2012 in “Cancer research” This study reports that side-population stem cells, distinct from hair follicle stem cells, may play a significant role in the malignant progression of squamous cell carcinomas in mice.
2 citations
,
July 2023 in “Journal of Education Health and Sport” This review article summarizes potential side effects of microneedle mesotherapy, including both infectious and non-infectious complications such as bruises, swelling, anaphylaxis, and skin necrosis, emphasizing that awareness and proper technique may mitigate these risks.
2 citations
,
June 2021 in “Immunopathologia Persa” This study observed that among Iranian patients with rheumatoid arthritis, methotrexate treatment was discontinued or reduced in nearly half of the cases due to side effects such as nausea, flu-like symptoms, hepatotoxicity, and hair loss, with hepatotoxicity linked to higher doses and longer treatment duration.
This study found that perceptions of scalp micropigmentation and awareness of its side effects vary significantly by gender and age, influencing attitudes and intentions toward the procedure.
November 2025 in “Cureus” This study found that COVID-19 vaccines were generally well-tolerated among Bangladeshi medical students, with most side effects being mild and decreasing in frequency after subsequent doses.
September 2025 in “Journal of the American Academy of Dermatology” This study explores patients' perceptions of hair loss treatments, specifically oral minoxidil, topical minoxidil, and oral finasteride, building on existing clinical research.
July 2024 in “Skin Appendage Disorders” In this study, researchers found that low-dose oral minoxidil for androgenetic alopecia in men generally showed a good safety profile, with hypertrichosis being the most frequent side effect, while systemic side effects like dizziness and hypotension were less common and no life-threatening effects were observed.
This observational study reviewed thyroid eye disease patients treated with teprotumumab at one center, reporting common side effects like fatigue and dry eye symptoms, with serious adverse events including two cases of blood clots and one pulmonary embolism.
January 2023 in “Side effects of drugs annual” This chapter reviews emerging side effects of various nutritional supplements and alternative medicine practices, highlighting potential toxicities and stressing the need for careful identification and management by healthcare professionals.
November 2020 in “Universal Journal of Pharmaceutical Research” In this study, tacrolimus-based treatment was found to result in fewer overall side effects compared to cyclosporine among Yemeni kidney transplant patients, although tacrolimus was associated with a higher incidence of diabetes.
July 2020 in “Scholars journal of applied medical sciences” This study found that vomiting was the most common side effect of sodium valproate in children under two with epilepsy.
April 2020 in “The Egyptian Journal of Plastic and Reconstructive Surgery” In this retrospective study of 29 patients with scalp burn alopecia, researchers utilized a simple method involving tissue expansion to reconstruct the temporal and lateral sideburn areas, resulting in satisfactory, symmetrical, and standardized aesthetic outcomes according to both objective and subjective evaluations.
This study describes a computational method using side-effect data from social media to identify new drug indications, suggesting it could be effective for drug repositioning.
7 citations
,
June 2020 in “Translational Andrology and Urology” This study evaluated potential penile vascular changes and persistent adverse effects in men discontinuing 5α-reductase inhibitors for androgenic alopecia, but no new clinical results were reported.