Side Effects’ Frequency Assessment of Low Dose Oral Minoxidil in Male Androgenetic Alopecia Patients

July 2024 in “ Skin Appendage Disorders ”

Leila David Bloch, Ruth C. Carlos

low dose oral minoxidil androgenetic alopecia hypertrichosis edema periorbital edema tachycardia insomnia Rogaine

TLDR Low dose oral minoxidil is safe for treating hair loss in men.

The study assessed the side effects of low dose oral minoxidil in 100 male patients with androgenetic alopecia. The most common side effect was body and facial hypertrichosis, while other observed side effects included lower legs edema, periorbital edema, fatigue, tachycardia, and insomnia. Expected side effects like dizziness, hypotension, respiratory changes, and diarrhea were not found. No life-threatening adverse effects were reported, indicating that low dose oral minoxidil has a good safety profile for treating hair loss.

View this study on karger.com →

Discuss this study in the Community →

Research cited in this study

3 / 3 results

research Review of Oral Minoxidil as Treatment of Hair Disorders: In Search of the Perfect Dose

21 citations, March 2021

Oral minoxidil effectively treats hair loss, with women needing lower doses (0.25 to 2.5 mg daily) and men needing higher doses (1.25 to 5 mg daily).

research Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients

39 citations, February 2021 in “Journal of The American Academy of Dermatology”

Low-dose oral minoxidil safely treats hair loss, with hypertrichosis as main side effect.

Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment

research Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment

24 citations, September 2020 in “Dermatology and therapy”

Oral minoxidil 5 mg daily increases hair growth safely in men with hair loss, with minor side effects.

Related Community Posts Join

6 / 1000+ results

community The no BS guide to saving your hair without finasteride (improvement in 90% of patients in the study) with a low side effect profile or improvement in 100% of patients but a higher side effect profile and increased dosage. The future is here?

in Minoxidil 92 upvotes 4 years ago

Hair loss treatments, specifically the use of oral minoxidil in combination with micro-needling. Oral minoxidil has been found to improve hair density in 90% of patients with a low side effect profile, but using 5mg per day can result in higher side effects including hypertrichosis and edema. Other treatments mentioned include finasteride and RU58841.

community Study Shows That Oral Minoxidil Is Not Only Good At Improving Hair But Also Reducing Arterial Stiffness And Preventing Other Health Problems

in Minoxidil 22 upvotes 3 years ago

Oral minoxidil may improve hair growth, reduce arterial stiffness, and prevent other health issues. Some users believe it is an effective treatment despite concerns about its effects on skin and blood.

community 15 Week Update of Oral Consumption of Topical Minoxidil. 3 drops Keeps 5% (3.75mg) 2x per day with comparison.

in Update 2 years ago

CumShotDiva's update on using topical minoxidil orally in an attempt to regrow hair, which has been met with both support and criticism from other users. The conversation includes discussion of possible side effects and the efficacy of this approach.

community hairline resurrection — 2 months before/after [5mg oral minoxidil, 1mg finasteride everyday, 2% keto shampoo every three days, weekly 0.5mm dermarolling]

in Progress Pictures 478 upvotes 1 year ago

This conversation was about a user named Substantial_Pen_1099 who has been using an regimen of 5mg oral minoxidil, 1mg finasteride everyday, 2% keto shampoo every three days, and weekly 0.5mm dermarolling for hair loss treatment over the course of 3 months. Others in the conversation expressed disbelief at their progress, to which Substantial_Pen_1099 provided video proof as evidence.

community Bryan (the guy who reversed aging) shares treatment that reversed his hair loss

in Treatment 1079 upvotes 1 month ago

A person improved hair loss from Norwood 3 to Norwood 2 using a topical formula with minoxidil, dutasteride, and tretinoin, plus oral minoxidil and red light therapy. There is skepticism about the treatment's effectiveness and concerns about misleading comparison photos.

community I’m going balls to the wall with probably the most nuclear stack apart from hormone blockers, will update this thread monthly.

in Treatment 52 upvotes 2 years ago

A user experimenting with an extreme hair loss treatment stack of Dutasteride, RU58841, 15 mg oral minoxidil, and microneedling, which sparked a debate among other users about the safety of this approach.

Related Research

1 / 1 results

Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia

research Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia

August 2023 in “Journal of Cosmetic Dermatology”

Some plants like spinach, broccoli, and matcha may boost the effectiveness of the hair growth drug minoxidil.