Side Effects and Possible Complications of Oral Contraceptive Drugs

The document discussed various side effects and complications associated with oral contraceptive drugs, which were most pronounced during the initial months of use. Common reactions included nausea, dizziness, headache, and depression, often attributed to the estrogenic component. Other issues included breast tenderness, intermenstrual spotting, and changes in menstrual patterns. Some users experienced skin reactions, hirsutism, and changes in weight. Serious concerns involved vascular complications, hepatic dysfunction, and potential thyroid function deviations, though no clinical signs of hyperthyroidism were noted. Oral contraceptives were linked to altered cortisol levels and reversible suppression of ovarian activity. Despite fears of carcinogenesis, no conclusive evidence was available at the time, and the long-term safety of these drugs required further study.