Disorder of Hair Growth in Hyperprolactinemia

    January 1988 in “ PubMed ”
    C.E. Orfanos, H. Hertel
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    TLDR High prolactin levels can cause skin and hair symptoms similar to those caused by hormone imbalances.
    In 1988, a study was conducted on five female patients aged 25-35 years who were experiencing hair loss and other symptoms such as hypertrichosis, disturbances of cyclic bleeding periods, secondary amenorrhea, galactorrhea, seborrhea, and acne. These patients were found to have functional hyperprolactinemia, a condition characterized by elevated levels of the hormone prolactin. Other hormonal parameters, including testosterone levels and thyroid gland function tests, were unchanged. Prolactinoma, a type of noncancerous tumor of the pituitary gland, was ruled out through x-ray diagrams and computer tomograms. The study concluded that cutaneous symptoms such as seborrhea, acne, hypertrichosis/hirsutism, and alopecia (collectively known as SAHA syndrome) may occur in hyperprolactinemia, mimicking androgen-induced skin symptoms. Therefore, in such cases, evaluation of prolactin levels along with androgen blood levels and thyroid gland function tests should be performed to exclude underlying endocrinopathy.
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      community does lowering your prolactin levels regrow hair?

      in Research/Science  11 upvotes 1 year ago
      The potential of lowering prolactin levels to regrow hair, with a reference to Bayer's drug HMI 115 which has been indicated as having this effect. Treatments mentioned include Minoxidil and Finasteride, as well as RU58841.

      community how about progesterone cream?

      in Research/Science  21 upvotes 6 months ago
      Progesterone cream might help with hair loss by inhibiting DHT production and suppressing prolactin, which can increase DHT. Some dermatologists have used progesterone for hair loss treatment, and it has been effective, sometimes combined with minoxidil, finasteride, and hydrocortisone.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  40 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community hmi115 is coming. Prepare yourselves for what's coming

      in Technology  106 upvotes 1 year ago
      The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

      community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

      in Update  36 upvotes 5 years ago
      The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

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    6 / 6 results