September 2022 in “International Journal of Science and Research (IJSR)” This study evaluated a pumpkin seed oil hair gel formulated with various additives and found that the F3 formulation had promising physicochemical properties and non-irritant characteristics for potential use in treating androgenetic alopecia.
September 2022 in “Tạp chí Y Dược học Cần Thơ” This study found that using grapefruit essential oil improved hair growth and length in a shaved white mice model compared to controls.
14 citations
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July 1977 in “Archives of Dermatology” This case report found that a linoleic acid topical application reversed essential fatty acid deficiency and improved scalp dermatitis, alopecia, and hair depigmentation in a 19-year-old patient on fat-free intravenous nutrition.
3 citations
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October 2018 in “International Journal of Green Pharmacy” This study suggested that an herbal shampoo containing Piper betle and Psidium guajava leaves extract may promote hair growth due to its antioxidant properties and showed stability for two months.
December 2023 in “Gugje bogeon mi-yong haghoeji” In this study, researchers observed that aroma oil-enhanced scalp scaling significantly improved scalp conditions over 8 weeks, marked by increased water and oil content, reduced keratin and surface value, and higher satisfaction in hair-related outcomes compared to the control group.
30 citations
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June 2008 in “Dermatologic Surgery” In this study, the SAFE System for follicular unit extraction demonstrated a favorable average follicle transection rate of 6.14% and is accessible for physicians with basic technical skills, showing promise for wider adoption.
1 citations
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November 2023 in “Contact dermatitis” In this study, sensitization to ethylhexyl salicylate was found in 27.3% of patients with frontal fibrosing alopecia, suggesting it may be a potential contact allergen for this condition.
March 2026 in “Scientific Reports” This study found that Cnidium officinale extract and its compound ferulic acid improved hair growth by promoting dermal papilla cell function and mitochondrial activity, suggesting their potential as a new treatment option for alopecia, possibly through estrogen receptor alpha activation.
August 2026 in “Molecules” This study found that Eucommia ulmoides bark extract shows potential antioxidant and hair follicle-support properties in vitro and in vivo, but further validation is needed to confirm these effects.
July 2023 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)” This study evaluated the resin oil of Copaifera officinalis L., identifying 64 compounds and developing validated analytical methods for quality control, and formulated a stable pharmaceutical foam, laying groundwork for potential clinical applications of copaiba oil.
1 citations
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August 2023 in “Austin Chemical Engineering” In this study, researchers developed hair and foot care products using tofu whey instead of water, highlighting its potential to conserve water and utilize protein-rich waste, though specific efficacy results are not reported.
September 2024 in “Sasambo Journal of Pharmacy” This study formulated and tested a pomegranate leaf shampoo with antifungal properties, identifying an optimal composition of 5.5% SLS and 15.5% cocamide DEA, showing good foam stability, appropriate pH, and viscosity in lab tests.
2 citations
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June 2017 in “ScienceRise” This study developed a mask-cream containing Sabal palm extract and Sophora japonica tincture for androgenic alopecia prevention and treatment, establishing optimal production techniques using a reverse emulsion method.
December 2023 in “Redox biology” In this study, DMC selectively eliminated senescent cells in old mice, prevented hair loss, improved motor coordination, and reduced senescence-associated secretory factors, suggesting its potential as a senolytic treatment.
July 2025 in “International Journal of Biological Macromolecules” Fucoidan may help regrow hair and reduce inflammation in hair loss.
16 citations
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August 2014 in “Archives of Pharmacal Research” This study found that surface-modified liquid crystalline nanoparticles significantly enhanced skin permeation of finasteride and dutasteride compared to unmodified nanoparticles, suggesting potential for improved treatment efficacy in androgenetic alopecia.
9 citations
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October 2024 in “Food Science and Biotechnology”
January 2023 in “International journal of pharmacognosy and clinical research” This study formulates a polyherbal hair oil using natural ingredients like curry leaves and fenugreek seeds and evaluates its physical and chemical properties, but reports no clinical results.
November 2024 in “Journal of Investigative Dermatology” Ursolic and shikimic acid together boost hair growth better than alone.
November 2024 in “Indus journal of bioscience research.” In this animal study, funnel seed extract significantly reduced insulin and testosterone levels and increased ovulating hormones in rats with induced polycystic ovarian syndrome, suggesting potential hormone-regulating properties.
1 citations
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August 2024 in “PubMed” This study found that Zhuangyao Jianshen pill significantly improved prostate health in testosterone-induced benign prostatic hyperplasia in castrated rats by modulating sex hormones and reducing inflammation and oxidative stress.
61 citations
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July 2022 in “Journal of Nanobiotechnology” This study found that carbon dots derived from fucoidan effectively inhibit Enterococcus faecalis and its biofilm, offering a promising approach for managing biofilm-associated persistent endodontic infections.
December 2024 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This case report describes a 62-year-old female patient with onycholysis whose condition recurred despite taking Coix seed extract, although both initial and recurrent symptoms resolved with its use, suggesting limited efficacy and warranting further study.
March 2004 in “大韓韓醫學會誌 = Journal of Korean Oriental Medicine” This review discusses two FDA-approved drugs for androgenetic alopecia, finasteride and minoxidil, and reports no new research findings.
This review concludes that the global literature supports the efficacy and safety of lipidosterolic extract of Serenoa repens in treating lower urinary tract symptoms, comparable to alpha-blockers and 5α-reductase inhibitors.
This study found that pectin lyase-modified red ginseng extract (GS-E3D) may promote hair growth by enhancing antioxidant and anti-inflammatory effects, proliferating hair dermal papilla cells, and inhibiting 5α-reductase activity.
11 citations
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January 2006 in “International Journal of Cosmetic Science” Some oils can penetrate hair and reduce the stickiness between fibers, but mineral oil cannot.
January 2014 in “Journal of Central South University(Science and Technology)” This study found that poly(propylene carbonate maleate) microspheres can successfully prolong finasteride release over 42 days, showing potential for long-term sustained drug delivery.
12 citations
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January 1988 in “YAKUGAKU ZASSHI” This study found that Polygonum multiflorum and Panax japonicum extracts could promote hair regrowth in mice, suggesting potential use as hair tonics.
June 2025 in “Unram Medical Journal” This review found that linoleic acid, when used in various skincare product formulations such as creams and serums, offers potential benefits for skin regeneration and hair growth, highlighting its promise as a natural, sustainable ingredient in cosmetics.