Effects of a Hair Essence Product Containing Five Herbal Extracts (HHRHG0202-80) on Hair Growth and Alopecia Prevention In Vitro and In Vivo

March 2004 in “ 大韓韓醫學會誌 = Journal of Korean Oriental Medicine ”

박원석, 성대석, 김대권, 조원희, 이해광, 이창훈, 박성규, 심영철

androgenetic alopecia 5α-reductase dermal papillae cells Glycyrrhizae radix Corni fructus Coicis semen Biotae semen hair essence product HHRHG0202-80 male pattern baldness hair growth alopecia prevention

TLDR The hair essence product promotes hair growth and prevents hair loss.

The study evaluated the effects of a hair essence product (HHRHG0202-80) containing five herbal extracts on hair growth and alopecia prevention, focusing on androgenetic alopecia. It tested the induction of mitosis in dermal papillae cells and the inhibition of type 2 5α-reductase. Three extracts (Glycyrrhizae radix, Corni fructus, and Coicis semen) significantly stimulated cell proliferation, while Biotae semen, Glycyrrhizae radix, and Coicis semen inhibited 5α-reductase activity. The product enhanced hair growth in C57b1/6 mice and inhibited alopecia in AGA mice, indicating its potential as a remedy for male pattern baldness and other alopecia conditions.

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