474 citations,
January 2012 in “Chemistry & biology” Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
182 citations,
November 2017 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
2 citations,
September 2015 in “Journal of the Egyptian Women's Dermatologic Society (Print)” People with psoriasis and depression have lower BDNF levels, which could help measure depression in those with psoriasis.
26 citations,
May 2021 in “International Journal of Molecular Sciences” Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.
17 citations,
July 2017 in “Molecular and Cellular Endocrinology” Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.
June 2023 in “Journal of multidisciplinary sciences (Online)” PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.
68 citations,
July 2011 in “Journal of Biochemistry/The journal of biochemistry” New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.
51 citations,
January 2007 in “Animal Genetics” The gene for slick hair in Senepol cattle is located on chromosome 20 and may involve the SRD5A2 gene.
14 citations,
June 2021 in “Expert Opinion on Therapeutic Patents” New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.
13 citations,
January 2017 in “Cosmetics” Different tests are used to see how hair care products affect hair, and choosing the right test is important for accurate results.
124 citations,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
1 citations,
January 2023 in “Metabolites” Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.
January 2024 in “Authorea (Authorea)” Using laccase to add poly(tyrosine) to wool makes it less likely to shrink and stronger.
2 citations,
August 2023 in “Life” Bioinspired polymers are promising for advanced medical treatments and tissue repair.
160 citations,
April 2014 in “Drug discovery today” Melatonin helps regulate sleep and may aid in treating various health issues.
25 citations,
October 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Mouse profilaggrin helps in skin cell differentiation and may be involved in calcium signaling.
22 citations,
July 2020 in “iScience” Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.
8 citations,
July 2022 in “International Journal of Molecular Sciences” Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.
8 citations,
July 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Curly hair is mechanically different from straight hair and may need new testing methods.
11 citations,
November 1998 in “Journal of dermatological science” Knocking out certain genes in mice helps understand skin and hair growth problems.
107 citations,
June 1997 in “PubMed” EGFR is essential for normal hair development and follicle differentiation.
12 citations,
June 2023 in “International Journal of Molecular Sciences” Innovative biomaterials show promise in healing chronic diabetic foot ulcers.
3 citations,
May 2023 in “Biomedicines” PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
August 2024 in “Cosmetics” Personalized treatments for hair loss are becoming more effective by using genetic information.
Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.
June 2015 in “Han'gug eung'yong saengmyeong hwa haghoeji/Journal of the Korean Society for Applied Biological Chemistry” Some synthesized peptides improved cell growth better than thymosin β4, VEGF, and minoxidil.
10 citations,
January 2016 in “Elsevier eBooks” Nanoparticles can speed up wound healing and deliver drugs effectively but may have potential toxicity risks.
40 citations,
November 2016 in “Molecules” Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.
1 citations,
January 2015 in “Hair therapy & transplantation” Some supplements and hormones can increase hair loss by raising DHT levels.
434 citations,
October 2003 in “PTR. Phytotherapy research/Phytotherapy research” Natural products in cosmetics are beneficial for skin and hair care with low toxicity.