188 citations
,
December 2020 in “Foods” This review explores the potential health benefits of food bioactive compounds, specifically polyphenols, as preventive agents against non-communicable diseases like cancer and cardiovascular disorders, while also addressing challenges like bioavailability and industrial applications.
188 citations
,
February 2023 in “International Journal of Molecular Sciences” This review compiled evidence suggesting that flavonoids may promote skin wound healing due to their anti-inflammatory, angiogenesis, re-epithelialization, and antioxidant properties, while also discussing current limitations and future prospects for these compounds as wound-healing agents.
128 citations
,
January 2023 in “Frontiers in Endocrinology” This review discusses recurrent implantation failure (RIF) in IVF, noting the lack of standard definitions or treatment protocols, and emphasizes the need for individualized treatment and further research.
111 citations
,
April 2023 in “Ultrasonics Sonochemistry” This review discusses the extraction, purification, and biological activities of maidenhairtree polysaccharides, emphasizing the higher efficiency of ultrasound-assisted extraction, but it reports no new clinical results.
79 citations
,
November 2016 in “EMBO Reports” This review evaluates methods to study stem cell division patterns, particularly in the mammary gland, and discusses genetic factors affecting division modalities and their implications for breast cancer, but reports no new results.
71 citations
,
February 2012 in “The American Journal of Human Genetics” This study found that a heterozygous missense mutation in ATR is associated with a hereditary cancer syndrome, manifested by oropharyngeal cancer and other anomalies, in an autosomal-dominant inheritance pattern across a five-generation family.
57 citations
,
May 2021 in “Molecules” This review explores the chemical composition and biological activities of essential oils from selected aromatic roots, highlighting their potential for various industries, though more research is needed to standardize their bioactive components.
54 citations
,
June 2018 in “Nutrients” This review discusses the diverse extra-intestinal manifestations of celiac disease in children and reports no new clinical results; the authors note differences in symptom prevalence and resolution compared to adults.
52 citations
,
January 2023 in “Annual Review of Immunology” This review discusses how immune mechanisms contribute to the regeneration and repair of epithelial tissues and highlights their potential role in both disease and therapeutic innovation; it reports no new clinical results.
47 citations
,
April 2021 in “BMC Medical Genomics” This systematic review and meta-analysis reported potential risk variants for acne in genes related to inflammation and sebaceous gland function, including TNF, CYP17A1, and FST, across diverse populations.
29 citations
,
February 2022 in “Frontiers in Cell and Developmental Biology” This review discusses strategies to improve CRISPR/Cas systems by addressing limitations like off-target effects and delivery inefficiencies, offering practical guidance and highlighting future applications, but reports no new research findings.
28 citations
,
December 2016 in “Journal of Biomedical Materials Research Part A” This study found that mesenchymal progenitor cells from human hair roots seeded onto polymer scaffolds stimulated the production of mineralized proteins, enhancing bone-like structures, with optimal results at a pore size of 35 µm.
25 citations
,
March 2024 in “Sustainability” This paper discusses strategies for creating sustainable cosmetic emulsions, highlighting the use of food waste, fermentation processes, and low-energy emulsification methods to minimize carbon footprint while preserving the bioactive properties of raw materials.
24 citations
,
October 2022 in “Cell Regeneration” This study describes a new mouse model for vitiligo that mimics key clinical features such as skin depigmentation and CD8 + T cell infiltration, providing a useful tool for in-depth research and drug discovery.
21 citations
,
November 2022 in “Clinical Cosmetic and Investigational Dermatology” This review highlights the potential of several medicinal plants as treatments for seborrhea dermatitis by inhibiting Malassezia growth and reducing symptoms like itching and redness, amid challenges of drug adherence and side effects in existing therapies.
18 citations
,
December 2021 in “Foods” This study explores the potential of seaweeds as a source of bioactive compounds for food, cosmetics, and medical applications, while highlighting concerns about toxic element accumulation and suggesting purification and nanoencapsulation techniques to enhance safety and stability.
18 citations
,
October 2022 in “Biomedicines” This review presents clinical and preclinical evidence supporting innovative regenerative approaches to treat vitiligo, as existing treatments lack a specific cure and predictable long-term repigmentation outcomes.
16 citations
,
April 2025 in “Foods” This study highlights the diverse applications of *Perilla frutescens* in traditional medicine, cuisine, and industrial settings, noting its significant antioxidant and antimicrobial properties in experimental models, as well as research efforts to enhance its bioactive content and ensure safety and standardization.
15 citations
,
January 2015 in “Stem cells international” This study found that erythrocytes can be generated from human hair follicle mesenchymal stem cells with OCT4 expression, potentially serving as an alternative source for transfusions.
12 citations
,
December 2023 in “Antioxidants” In this study, researchers found that blackberry leaves exhibited higher liposoluble antioxidant levels and inhibited lipid peroxidation more effectively than raspberry leaves, while raspberry leaves showed greater water-soluble antioxidant content and hydroxyl radical inhibition in vitro.
12 citations
,
October 2021 in “Cells” This review discusses the potential of miRNA-mediated hair growth treatments for androgenetic alopecia by targeting DKK1 to modulate the Wnt/β-catenin signaling pathway and reports no new clinical findings.
12 citations
,
January 2021 in “Journal of Investigative Dermatology” This review discusses the role of telomere length dynamics in hair follicle biology and reports no new clinical findings, emphasizing the need for further research in humans.
11 citations
,
December 2021 in “Journal of Ginseng Research/Journal of ginseng research” This review discusses the chemical composition, potential health benefits, and extraction methods of red ginseng oil, and reports no new clinical results but emphasizes safety and proposed molecular mechanisms.
11 citations
,
January 2018 in “IET Nanobiotechnology” In this study, poly (ɛ-caprolactone)–chitosan–poly (vinyl alcohol) nanofibrous scaffolds used on canine skin wound models were found to significantly accelerate healing rates of excision and burn wounds, without inducing immunogenic reactions.
10 citations
,
September 2023 in “Metabolites” This study reviews iron metabolism in the skin, highlighting how differentially expressed genes regulate iron recycling in the epidermis, and discusses changes in iron metabolism related to skin diseases.
9 citations
,
June 2022 in “Reviews in Environmental Science and Bio/Technology” This review discusses the industrial applications of maritime pine by-products, emphasizing their antioxidant and antimicrobial properties, and suggests innovation opportunities in a circular economy context; it reports no new results.
9 citations
,
May 2025 in “Stem Cell Research & Therapy” This review discusses how extracellular vesicles play a dual role in age-related diseases by contributing to both disease pathogenesis and potential therapeutic strategies through the transfer of specific molecules.
8 citations
,
May 2023 in “Gels” This review discusses the advantages and progress of chitosan hydrogels in vascular regeneration for tissue engineering scaffolds, highlighting modifications to enhance their application and exploring future prospects.
8 citations
,
August 2014 in “Journal of Clinical Oncology” This article explores the historical development and evolution of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT), emphasizing advancements in safety and technology, and reports no new clinical results.
7 citations
,
January 2017 in “Stem Cells International” This review categorizes current research on neural organogenesis and highlights potential future applications for treating central nervous system diseases, but reports no new clinical results.