Extra-Intestinal Manifestation of Celiac Disease in Children

The document reviewed various studies on the extra-intestinal manifestations of celiac disease (CD) in children, including dermatological, dental, bone, neurological, psychiatric, and joint issues. Common manifestations included dermatitis herpetiformis, dental enamel defects, growth failure, short stature, iron-deficiency anemia, and alopecia. The studies emphasized the importance of early diagnosis and strict adherence to a gluten-free diet (GFD) for symptom resolution and optimal recovery. Children generally showed faster and greater improvement on a GFD compared to adults. The findings highlighted the need for healthcare providers to consider CD in the differential diagnosis when children present with non-gastrointestinal symptoms.