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Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Finasteride affects prostate development differently in male and female Mongolian gerbils.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Older adults still engage in sexual activities but face challenges like health issues and lack of professional support, highlighting the need for better healthcare provider education and research on sexual fulfillment in old age.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Oral zinc therapy is effective for treating acrodermatitis enteropathica.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.

Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

The document concludes that diagnosing PCOS requires a thorough approach, considering various symptoms and risks, and calls for improved methods to identify PCOS types and prevent diabetes.

Skin problems like acne and excess hair in PCOS are common and linked to being overweight.