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Loss of keratin K2 causes skin problems and inflammation.

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

Finasteride reduces new brain cells in male mice, possibly causing depression.

Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.

Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.

Sarcoptes scabiei infection causes significant health and behavior changes in wombats.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.

The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.

The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.

Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.

The study tested a hair treatment and found it can help grow hair, but won't stop baldness. It's safe and works well, but needs more testing.

Late pregnancy helps repair brain damage in rats due to the GABAergic system.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

Young women with high male hormone levels or PCOS often feel more psychological distress and have a lower quality of life.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.

South Asian women with PCOS present with different symptoms compared to White women, influenced by ethnicity, obesity, and age.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.