Different genes and pathways are active in yak skin and hair cells, affecting hair growth and immune responses.
489 citations,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
488 citations,
July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
186 citations,
December 2012 in “Current opinion in cell biology” Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
129 citations,
July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
51 citations,
September 2012 in “Biomacromolecules” Disulfide bonds make keratin in hair stronger and tougher.
13 citations,
April 2018 in “Scientific Reports” The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.
12 citations,
October 2018 in “Biotechnology reports” Recombinant keratin K31 makes damaged hair thicker, stronger, and straighter.
9 citations,
November 2020 in “The FASEB journal” Intermediate filaments are crucial for cell differentiation and stem cell function.
8 citations,
February 2021 in “Biomolecules & therapeutics” Myristoleic acid helps hair growth by boosting cell growth and recycling processes in hair follicle cells.
7 citations,
January 2023 in “Journal of Hematology & Oncology” Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
6 citations,
June 2012 in “PloS one” A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.
6 citations,
January 2012 in “Hair transplant forum international” Best solution for storing hair grafts is saline with ATP at 4 degrees Celsius, but no definitive best method was confirmed.
5 citations,
October 2022 in “Phenomics” Your skin is like an ecosystem, with its own community of microbes and substances that interact and affect its health.
5 citations,
April 2022 in “Frontiers in Medicine” Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
2 citations,
June 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Epigenetic factors play a crucial role in skin health and disease.
1 citations,
January 2021 in “European Journal of Inflammation” Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.
January 2025 in “Cellular and Molecular Life Sciences” BMP4 helps stem cells turn into pigment-producing cells, affecting hair color and growth.
February 2024 in “Epigenomes” Epigenetic mechanisms control skin development by regulating gene expression.
February 2024 in “Neurophotonics” Light therapy on the brain shows promise for treating brain diseases and improving brain function.
December 2023 in “Animals” The research found genes and miRNAs that may control hair growth in Forest Musk Deer.
December 2023 in “Animals” The study mapped yak skin cells to understand hair growth better.
March 2023 in “Scientific Reports” Using focused ultrasound on the brain can help epilepsy medicine work better in rats.
January 2022 in “Stem cell biology and regenerative medicine” New biofabrication technologies could lead to treatments for hair loss.
January 2022 in “Sustainable development goals series” The document concludes that significant investment in agricultural innovation is necessary to achieve global food security and nutrition.
November 2021 in “Dermatology Research and Practice” The study aims to understand the skin and hair characteristics of mothers and their babies, and how these may affect newborns' skin health and mothers' postpartum hair loss.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
39 citations,
November 2015 in “Nanomedicine” Improved Finasteride delivery for hair loss treatment.
15 citations,
July 2021 in “JAMA Dermatology” Androgenetic alopecia negatively affects quality of life and self-esteem, especially in women, but not depression.
4 citations,
May 2023 in “Composites Part B: Engineering” The nanocomposite hydrogels can repair themselves, change shape, reduce inflammation, protect against oxidation, kill bacteria, stop bleeding, and help heal diabetic wounds while allowing for wound monitoring.