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A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.

Skin heals with scars because only one type of fibroblast is used, not a mix.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

TGF-β2 plays a key role in human hair growth and development.

Whale genes show changes that help them live in water, like less hair and better flippers.

A special environment is needed to fully activate sleeping stem cells.

Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.

The research identified genes that explain why some sheep have curly wool and others have straight wool.

Changes in the HR gene have influenced hair growth and may lead to hair loss conditions in humans.

Pantethine may boost the immune system's ability to fight sarcoma.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

HDAC inhibitors, like Vorinostat and Entinostat, can help regrow hair in alopecia areata.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Targeting colon cancer stem cells might lead to better treatment results.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Different types of skin cells play specific roles in development, healing, and cancer.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.