November 2025 in “Open Access CRIS of the University of Bern” This study compared serum and hair steroid hormone profiles in adolescents and found that hair steroid profiling is a feasible, non-invasive alternative to serum analysis, with androgen levels in both mediums correlating more strongly with body size and composition in boys than in girls.
June 2023 in “Benha Journal of Applied Sciences” This study observed that female patients with chronic telogen effluvium had significantly lower levels of total thiol, thiol-disulphide, and disulphide compared to healthy controls, indicating a disruption in oxidative stress balance.
72 citations
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April 2008 in “The Journal of urology/The journal of urology” This study found that 1-year use of 5alpha-reductase inhibitors, dutasteride or finasteride, significantly lowered dihydrotestosterone levels without adversely affecting bone density, lipids, or hemoglobin in normal men.
44 citations
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March 2008 in “European journal of endocrinology” This study found that women with PCOS had lower fasting serum ghrelin levels and a reduced ghrelin response to an oral glucose load compared to controls, with an inverse relationship to insulin resistance.
39 citations
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September 2017 in “The Open Rheumatology Journal” This review discusses the role of complement activation in SLE and suggests that while monitoring C3 and C4 remains important, increased levels of cell-bound complement activation products may better indicate disease activity.
11 citations
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January 2011 in “Turkish Journal of Medical Sciences” This study found that iron deficiency anemia is a key factor in the development of telogen effluvium, and higher 25-hydroxyvitamin D3 levels in TE patients may be linked to increased UV exposure.
5 citations
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May 2020 in “Diagnostics” This study involving male patients with androgenic alopecia found that a higher baseline zinc plasma level, specifically above 10 µmol/L, may predict the success of treatment with 5% topical minoxidil, correlating with increased hair density and diameter in the parietal area.
2 citations
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September 2015 in “Journal of the Egyptian Women's Dermatologic Society (Print)” People with psoriasis and depression have lower BDNF levels, which could help measure depression in those with psoriasis.
August 2024 in “Archives of Women s Mental Health” This study found that women with PCOS exhibited higher levels of depression, tension induction, and impaired stress coping strategies compared to healthy controls, with these psychological issues correlating with hyperandrogenism but not with central obesity or insulin resistance.
June 2024 in “Research Square (Research Square)” This study found that women experiencing hair loss post-COVID-19 showed significantly decreased serum copper levels, suggesting potential further research into copper supplementation for preventing and treating post-COVID-19 alopecia.
May 2024 in “International journal of research in dermatology” This study found that vitamin D deficiency was significantly more prevalent among men with androgenetic alopecia in eastern Uttar Pradesh, India, than in age-matched controls, suggesting a potential link between vitamin D levels and the condition's pathogenesis.
January 2019 in “Menoufia Medical Journal” This study found that women with female pattern hair loss had significantly lower serum vitamin D levels than healthy controls, suggesting a possible role of vitamin D deficiency in the condition.
July 2018 in “Benha Journal of Applied Sciences” This study found that patients with androgenetic alopecia had higher serum homocysteine levels, which were positively correlated with BMI and smoking, suggesting it could be an early predictor for AGA diagnosis.
54 citations
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June 2001 in “The Indian Journal of Pediatrics” This study found that newborns with neural tube defects and their mothers had significantly lower hair zinc levels compared to controls.
30 citations
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January 2008 in “The Aging Male” This study found no difference in male pattern baldness between patients with benign prostate hyperplasia and prostate cancer, and no correlation with serum androgen levels.
22 citations
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September 2008 in “Brain & development” In this study on rats, valproic acid was associated with reduced biotinidase enzyme activity and higher alopecia rates, but biotin supplementation did not significantly affect alopecia occurrence.
3 citations
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February 2013 in “Bangladesh Journal of Medicine” This study found that women with telogen effluvium were significantly associated with lower iron levels compared to those without hair loss.
3 citations
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December 1968 in “PubMed” This letter reports that serum iron levels and binding capacities were normal in women with androgenetic alopecia, suggesting that the condition may not be related to iron deficiency.
1 citations
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October 2020 in “Journal of Cosmetic Dermatology” In this study, premature hair graying in Egyptians was significantly linked to family history, stress, sedentary lifestyle, and low serum ferritin levels, but not to vitamin D deficiency.
1 citations
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December 1968 in “Archives of Dermatology” This letter reports that normal iron levels were observed in women with androgenetic alopecia, suggesting the condition may not be related to iron deficiency.
January 2026 in “Open Science Framework” In this study, network meta-analyses were used to explore the ranking of various 5-alpha reductase inhibitor regimens on reducing dihydrotestosterone levels and to investigate whether this reduction correlates with increased total hair density in male androgenetic alopecia.
October 2023 in “Acta dermato-venereologica (Print)” This study found that patients with severe alopecia areata had significantly lower serum zinc levels compared to healthy controls, and a negative correlation between zinc levels and disease severity was observed, suggesting that zinc assessment and supplementation trials may be warranted in this population.
This study found a correlation between zinc levels in hair and serum, and alkaline phosphatase activity in acne phlegmonosa and alopecia areata patients.
October 2025 in “Medical Journal of Babylon” In this study, researchers found that female COVID-19 patients experiencing hair loss had higher testosterone levels and lower Vitamin D levels than healthy controls, suggesting these hormonal factors may play a role in post-COVID-19 hair loss.
This study found no significant differences in iron metabolism-related or thyroid function parameters between women with chronic diffuse hair loss and healthy controls.
May 2023 in “Journal of Pakistan Medical Association” This study found that women with polycystic ovary syndrome had significantly higher levels of serum and follicular fluid Gremlin-1 compared to healthy controls, suggesting potential diagnostic utility for these biomarker levels.
33 citations
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September 2014 in “Reproductive Biology and Endocrinology” In this study, elevated afamin concentrations were associated with metabolic syndrome in young women, particularly those with insulin resistance, suggesting a potential predictive role for afamin in metabolic risk assessment.
176 citations
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August 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” In this study, cross-sex hormone therapy affected hair growth patterns differently, with estrogen reducing hair growth in male-to-female transsexuals and testosterone increasing it in female-to-male transsexuals; however, male typical hair diameters were not fully reached in the latter group after 12 months.
7 citations
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December 2014 in “Journal of dermatology” This study found that miR-221 levels in hair shafts were significantly higher in malignant melanoma patients compared to controls, suggesting potential as a non-invasive screening marker.
September 2024 in “African Journal of Biomedical Research” This study found that individuals with alopecia areata had significantly lower blood levels of vitamin D and slightly lower serum copper levels compared to healthy controls, suggesting the potential importance of assessing these factors in the chemical evaluation of patients with this condition.