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Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.

Light affects skin health, aging, and cancer risk, and new light-based treatments and imaging are promising for skin care.

The human sebocyte culture model has improved understanding of oily skin and acne, and how they can be treated.

C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.

Without keratin 10, there's more growth and development of oil-producing skin cells.

Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.

Y27632 increases cell growth through EGFR signaling, not ROCK1/2.

The endocannabinoid system affects oil production and inflammation in skin cells.

Deleting MPZL3 increases skin oil production and reduces body fat.

DHT may reduce inflammation caused by certain bacteria in skin cells.

Cow milk sugars increase fat production and inflammation in skin oil cells.

Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.

Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.

We now understand more about what causes acne and this could lead to better, more personalized treatments.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Sex hormones, especially androgens, play a key role in causing acne.

A20 protein is crucial for normal skin and hair development.

SCD1 is crucial for skin health and overall energy balance.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

Backhousia citriodora leaf extract effectively reduces oily skin across different ethnic groups.

The research found that a protein called PPARg is important for the formation and healing of sebaceous glands, which can regenerate independently from hair follicles.

Mouse skin glands need healthy nerves to grow properly during hair growth phases.

Sebaceous lipids are crucial for keeping skin and eyes healthy in mice.

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.