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This article reviews the protective and regenerative mechanisms of nerve fibers and Schwann cells after injury but reports no new findings.

This study demonstrated that keratin derived from human hair can improve axon extension and alleviate motor deficits from sciatic nerve injuries, highlighting its potential as a promising biomaterial for peripheral nerve regeneration.

This article discusses how recent research suggests that aggressive video games have little effect on aggression and violence among players, calling for professional organizations to update their policy statements accordingly.

This study examined the use of keratin gel as a filler in nerve guides for peripheral nerve regeneration in a rat sciatic nerve injury model.

This study suggests that hair follicle stem cells from transgenic mice can improve nerve regeneration and function, highlighting their potential as an autologous source for regenerative medicine.

In this study, transplantation of rat hair follicle stem cells significantly improved sciatic nerve regeneration and muscle function in nerve-injured rats.

This study reports that hair follicle stem cells, termed HAP stem cells, can differentiate into neuronal and glial cells, enhancing nerve repair and locomotor recovery after injury.

This rat study found that a PLGA conduit filled with neural crest stem cells derived from hair follicles showed promising results in repairing peripheral nerve injuries, partially restoring sensory function and improving nerve structure.

In this study, researchers explored how hair follicle neural crest stem cell-derived exosomes, particularly those carrying miR-214-3p, promote neurite outgrowth and aid peripheral nerve regeneration, supported by detailed in vitro and in vivo data on nerve repair and functional recovery in rat models.

This dataset supports a study suggesting that hair follicle neural crest stem cell-derived exosomes carrying miR-214-3p may promote neurite outgrowth and aid peripheral nerve regeneration in vitro and in vivo.

This report introduces a tissue-engineered nerve conduit combining hfNCSCs-derived neurons and acellular nerve grafts to potentially repair long-distance peripheral nerve injuries.

This study found that minoxidil may protect against chemotherapy-induced peripheral neuropathy and potentially support hair recovery and tumor suppression in mouse models.

This study found that pyramidal neural precursors best grew neurites on matrigel, while neural stem cells differentiated directionally on aligned fibrin, suggesting the importance of biomaterial selection for cell culture.

In this study, intrathecal progesterone administration initially worsened mechanical allodynia in mice after nerve injury, but later reduced pain when applied during the maintenance phase, highlighting distinct roles for cytochrome P450c17 and 5α-reductase in neuropathic pain modulation.

In this study, human hair follicle pluripotent stem cells transplanted into severed mouse sciatic nerves differentiated into Schwann cells and supported nerve regeneration, offering a promising alternative to embryonic or iPS cells for regenerative medicine.

In this study, the researchers found that a keratin hydrogel filler in nerve conduits led to earlier Schwann cell migration and improved cellular behaviors compared to other fillers in a rat sciatic nerve model.

This study suggests that nestin-expressing hair follicle stem cells, when transplanted into transgenic mice with sciatic nerve injury, can differentiate into motor neurons and reduce muscle atrophy.

This study found that using induced pluripotent stem cell-derived mesenchymal stem cells with acellular nerve allografts significantly improved axon regeneration and functional recovery in rats with sciatic nerve injuries, suggesting a promising approach for clinical nerve repair therapies.

This study found that transplanting human hair follicle pluripotent stem cells can promote the recovery of sciatic nerve function in a mouse model of nerve impingement.

This study found that human hair keratin bridges effectively induced nerve regeneration and demonstrated good biocompatibility and controlled degradation when used in rats with peripheral nerve defects.

This study found that human hair keratin can effectively induce peripheral nerve regeneration in rats, showing good biocompatibility and a controllable degradation rate when used as a scaffold material.

This study found no evidence supporting the hypothesis that Aβ afferents sprout into the superficial laminas of the spinal cord after nerve injury in rats.

This study found that hair-follicle-associated-pluripotent (HAP) stem cells can be cryopreserved for future use in nerve and spinal cord repair, with human trials being planned.

This study found that hair follicle stem cells can effectively enhance nerve regeneration and restore function in peripheral nerve injuries in mice, suggesting their potential as a source for autologous stem cell therapy.

In this study, hair follicle stem cells from ND-GFP transgenic mice were observed to be pluripotent, effectively repairing peripheral nerve and spinal cord injuries in mouse models.

This study found that compound 3, a tetrahydropyridoindole carboxymethylated at position 5, significantly inhibited sorbitol accumulation in both rat eye lenses and tissues affected by diabetes, indicating its potential as a lead compound for ALR2 inhibition.

This review discusses indole-based bifunctional aldose reductase inhibitors and antioxidants for diabetic complications and chronic inflammation-related pathologies, but reports no new clinical results.

In this study, researchers used NIR-II fluorescence imaging to track the survival and migration of EPI-NCSCs in rat models, finding that these stem cells aided in repairing facial nerve defects when applied via acellular nerve allografts.

This study found that macrophages play a crucial role in nerve regeneration by regulating Schwann cell dynamics and remyelination, with Gas6 identified as a key factor in this process.