research Hair loss
This article discusses treatments for male pattern baldness, noting that minoxidil is effective for improving baldness at the scalp vertex in young men, and reports no new clinical results.
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research Cosmetic Concerns Among Men
This review highlights men's cosmetic interests, focusing on maintaining a masculine appearance while managing scalp hair, facial lines, and other aging signs, but presents no new findings.
research The effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia
In this study, finasteride doses as low as 0.2 mg per day significantly reduced both scalp skin and serum DHT levels in men with androgenetic alopecia.
research Effects of a novel finasteride 0.25% topical solution on scalp and serum dihydrotestosterone in healthy men with androgenetic alopecia
This study found that applying a novel 0.25% finasteride solution to the scalp can effectively reduce scalp DHT levels in men with androgenetic alopecia, potentially reducing systemic side-effects.
research Androgenetic alopecia.
This article reviews current diagnostic and treatment approaches for androgenetic alopecia but reports no new results, focusing on its progression and medical management options.
research What Ages Hair?
This source summarizes discussions by an advisory board of twelve experts on hair loss, focusing on heredity, aging, and environmental impacts, and emphasizing strategies that may slow alopecia.
research The mRNA for Protease Nexin-1 is Expressed in Human Dermal Papilla Cells and its Level is Affected by Androgen
This study found that protease nexin-1 mRNA is expressed in human dermal papilla cells and is downregulated by dihydrotestosterone in balding scalp, suggesting a role in male-pattern baldness progression.
research Androgenic alopecia: A counterproductive outcome of the anabolic effect of androgens
This paper proposes a theory explaining how the normal anabolic effects of androgens lead to structural changes and hair follicle miniaturization, contributing to androgenic alopecia.
research Efficacy and Safety of a New Topical Hair Loss-Lotion Containing Oleanolic Acid, Apigenin, Biotinyl Tripeptide-1, Diaminopyrimidine Oxide, Adenosine, Biotin and Ginkgo biloba in Patients with Androgenetic Alopecia and Telogen effluvium: A Six-month Open-Label Prospective Clinical Study
This study found that a new hair loss lotion containing various cosmetic ingredients significantly increased total hair fibers and anagen hairs in individuals with androgenetic alopecia and telogen effluvium, while also improving visual hair characteristics and receiving positive user feedback without adverse effects.
research Herbal Oil Formulation for Managing Male Pattern Baldness (Alopecia)
This review examined a polyherbal hair formulation aimed at managing male pattern baldness, reporting that its ingredients may enhance scalp blood circulation, strengthen hair follicles, and promote hair regrowth through various mechanisms such as antioxidant and DHT-inhibiting effects.
research Herbal Oil Formulation for Managing Male Pattern Baldness (Alopecia)
This review reports on a polyherbal hair formulation developed to manage male pattern baldness, highlighting its potential to enhance scalp blood circulation, strengthen hair follicles, and promote hair regrowth through antioxidant, anti-inflammatory, and DHT-inhibiting mechanisms.
research Efficacy of Botulinum Toxin in Male Androgenetic Alopecia: a Triple-Blind, Randomized Clinical Trial
Botulinum toxin may help treat male pattern baldness.
research Sparse hair in a female toddler
Iron supplements may reverse premature graying in iron-deficient individuals; ingrown nails are common in diabetics with certain risk factors; topical finasteride may reduce scalp DHT as effectively as oral finasteride; monilethrix treatment is challenging but some medications can help.
research Nonscarring alopecias
This article discusses the genetic and hormonal factors contributing to male pattern hair loss but reports no new experimental results.
research Discriminating in favour of or against men with increased risk of finasteride-related side effects?
This review discusses the efficacy and safety of oral finasteride for treating male pattern baldness and the potential persistent side effects, but no new results are reported.
research Androgenetic alopecia
This article reviews the causes and pattern of androgenetic alopecia and reports no new research findings.
research Managing patterned hair loss – a hair raising task!
This review summarizes existing knowledge on diffuse and patterned alopecia, emphasizing recent advancements in treatment beyond FDA-approved options, but it reports no new clinical findings.
research 5α-Reductase Inhibitors, Chemical and Clinical Models
This study constructed a model to predict finasteride's inhibitory activity on 5α-reductase type 2 and calculated that a 1 μM plasma concentration, after 50 mg administration, matches prostate inhibition levels.
research Classification scale for male and female androgenetic alopecia.
Scale created to measure hair loss in men and women; MK-386 reduces acne; Niaspan treats dyslipidemia; minoxidil increases heart rate.
research Increased Scalp Skin and Serum 5a-Reductase Reduced Androgens in a Man Relevant to the Acquired Progressive Kinky Hair Disorder and Developing Androgenetic Alopecia
Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.
research Evaluation of androgens in the scalp hair and plasma of patients with male-pattern baldness before and after finasteride administration
This study found that finasteride decreases DHT/T levels more significantly in the vertex scalp hair than in the occipital hair of patients with male pattern baldness.
research Increased Androgen Binding Capacity in Sebaceous Glands in Scalp of Male-pattern Baldness
This study found that sebaceous glands in bald scalp have greater androgen binding affinity and capacity than those in hairy scalp, possibly contributing to the androgenic response seen in male pattern baldness.
research Minoxidil increases 17β-hydroxysteroid dehydrogenase and 5α-reductase activity of cultured human dermal papilla cells from balding scalp
This study found that minoxidil increased 17ß-hydroxysteroid dehydrogenase activity by nearly 40% in dermal papilla cells from balding scalps but not in nonbalding scalp cells or dermal fibroblasts.
research A novel finasteride 0.25% topical solution for androgenetic alopecia: pharmacokinetics and effects on plasma androgen levels in healthy male volunteers
This study found that both topical and oral finasteride significantly reduced plasma DHT after one week, with lower finasteride plasma exposure for the topical formulation.
research 5alpha-reductase inhibitors - a new hope in dermatology?
This article discusses the potential use of 5α-reductase inhibitors in dermatology and reports no new clinical results; the authors suggest further exploration of their dermatological applications.
research Androgens and alopecia
This study found that finasteride improves scalp hair growth in men with male pattern hair loss by reducing scalp dihydrotestosterone levels, but it did not benefit postmenopausal women with female pattern hair loss.
research Hair Restoration
The document concludes that there are various causes and treatments for hair loss, with hair transplantation being a notable option.
research A hypothetical pathogenesis model for androgenic alopecia: clarifying the dihydrotestosterone paradox and rate-limiting recovery factors
This review evaluates dihydrotestosterone's role in androgenic alopecia and proposes a model suggesting that chronic scalp tension and inflammation contribute to hair follicle miniaturization, identifying fibrosis, calcification, and tension as treatment targets.
research Rosmagain™ as a Natural Therapeutic for Hair Regrowth and Scalp Health: A Double-Blind, Randomized, Three-Armed, Placebo-Controlled Clinical Trial
In this clinical trial, rosemary-lavender and rosemary-castor oils were found to significantly improve hair growth rate, thickness, density, length, and reduce hair fall compared to coconut oil over 90 days, indicating they may be effective natural alternatives for hair regrowth.
research Effect of the multifunctional cosmetic ingredient sphinganine on hair loss in men and women with diffuse hair reduction
This study found that sphinganine may improve scalp health, hair quality, and reduce hair loss in males, potentially due to increased antimicrobial peptide levels and inhibition of 5-α-reductase.