January 2013 in “Anti-infection Pharmacy” This review discusses the pharmacological and dermatological uses of Ligustri Lucidi Fructus and its components, such as anti-inflammation, anti-allergy, anti-dermatotumor effects, and hair growth promotion, but reports no new clinical results.
June 2013 in “Revista cubana de plantas medicinales” This study found that Sida cordifolia collected in Colombia is a good source of steroidal saponins, which may contribute to its antioxidant and antifungal properties.
10 citations
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April 2013 in “Revista cubana de plantas medicinales” This study found that Sida cordifolia L. from Colombia is rich in saponins, which may contribute to its antioxidant and antifungal properties.
18 citations
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March 2024 in “Frontiers in Pharmacology” This review highlights that the NLRP3 inflammasome is a promising therapeutic target for cerebral ischemia-reperfusion injury and discusses recent advancements in using natural plant products to modulate this pathway and reduce inflammation.
August 2025 in “Processes” In this study, researchers used a network pharmacology approach to highlight significant interactions between compounds in rosemary (Salvia rosmarinus) and genes related to functional dyspepsia, suggesting potential pathways for developing treatments against gastrointestinal diseases.
138 citations
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July 2015 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses how Western diet may contribute to acne vulgaris through insulin signaling and metabolomic changes, promoting a dietary approach for management, but reports no new experimental results.
17 citations
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June 2020 in “Animals” This study identified differentially expressed mRNAs and lncRNAs in Hu sheep hair follicles, suggesting certain genes and pathways are involved in the development of wool curvature patterns.
15 citations
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April 2022 in “Biointerface Research in Applied Chemistry” This review presents current evidence on medicinal plants and their phytoconstituents, such as phenolic compounds, used in acne treatment, highlighting their potential as alternatives to conventional therapies due to issues like antibiotic resistance and high cost.
13 citations
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February 2019 in “Journal of Microencapsulation” This study focused on designing a niosome formulation that encapsulates pumpkin seed oil for topical use, achieving high entrapment efficiency and stability over three months.
12 citations
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June 2021 in “Scientific Reports” This study identified aging-related epigenetic and transcriptomic biomarkers and suggested that curcumin might target and inhibit the JUN gene, implicating potential therapeutic strategies against aging.
7 citations
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February 2025 in “Stem Cell Research & Therapy” In a study using a mouse model, HF-MSCs were reported to enhance ovarian function in cyclophosphamide-induced premature ovarian failure more effectively than HU-MSCs, potentially by preventing ferroptosis in granulosa cells via the KEAP1/NRF2/HO-1 pathway.
1 citations
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February 2022 in “Clinical and Experimental Health Sciences” In this study, dexpanthenol exhibited antiepileptic and antidepressant-like effects in mice without impacting their motor coordination.
1 citations
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January 2019 in “Advances in Medical Sciences” This study found that a combination of azelaic acid, minoxidil, and caffeine significantly reduced skin flap necrosis in rats, likely by increasing nitric oxide content and iNOS expression, compared to individual treatments.
April 2026 in “Frontiers in Pharmacology” This review systematically evaluates Erzhi Pill's formulation, therapeutic potential, and challenges, exploring its traditional applications and modern prospects for developing integrated quality control and precise medical strategies.
January 2025 in “Indian Journal of Animal Research” This study observed that herbal feed supplementation in Frieswal breeding bulls improved semen volume and motility, while significantly lowering dihydrotestosterone levels, suggesting a potential mechanism for enhancing semen quality.
October 2023 in “Frontiers in endocrinology” This review investigates molecular mechanisms behind PCOS pathogenesis and discusses potential therapies, but reports no new clinical results.
May 2022 in “Research Square (Research Square)” This review summarizes research on individual Chinese herbal extracts that may inhibit mechanisms of renal fibrosis, but it reports no new experimental findings.
13 citations
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October 2017 in “Bioorganic & Medicinal Chemistry” This study found that compound 3, a tetrahydropyridoindole carboxymethylated at position 5, significantly inhibited sorbitol accumulation in both rat eye lenses and tissues affected by diabetes, indicating its potential as a lead compound for ALR2 inhibition.
January 2026 in “Lumbung Farmasi Jurnal Ilmu Kefarmasian” This study found that a topical emulsion containing purified extracts of sidr leaves and roasted candlenut seeds significantly increased hair growth compared to the base and 2% minoxidil, potentially through their antioxidant and anti-inflammatory properties.
January 2026 in “Journal of Dermatological Science” This research observed that Salvianolic acid B (Sal B) significantly promoted hair regeneration in vivo and in vitro, outperforming minoxidil in a mouse model of androgenetic alopecia, by activating Wnt/β-catenin and mTORC2/Akt pathways and upregulating MMPs and MAPKs.
1 citations
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January 2022 in “Food & Function” This study found that fruit extracts from certain Egyptian Sabal species demonstrated significant anti-androgenic activity and potential therapeutic effects against benign prostatic hyperplasia in rat models and cell lines.
January 2026 in “RSC Medicinal Chemistry” This study notes the ongoing challenge in developing new drugs for androgenetic alopecia, mentioning that both minoxidil and finasteride were originally intended for treating hypertension. Results are not reported.
January 2026 in “Chemical Communications” This study found that calanthoside, a compound isolated from Calanthe species, promotes the proliferation of human hair follicle dermal papilla cells more effectively than minoxidil.
6 citations
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December 2022 in “Toxicological Research”
September 2023 in “Apple Academic Press eBooks” This review highlights that Salvia rosmarinus, commonly known as rosemary, possesses multiple pharmacological activities, such as antioxidant, anti-inflammatory, and anticancer effects, and is used in medicinal, cosmetic, and food products due to its rich bioactive components.
4 citations
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June 2020 in “Processes” This study suggests that G. sibiricum has potent aldose reductase inhibitory activity, primarily due to kaempferol rhamnosides, and may be further explored as a natural treatment for diabetes-related complications.
January 2009 in “Journal of Jilin Medical College” This study found that SDG did not significantly affect prostate weight in rats with BPH, but it may reduce serum PAP activity and alter prostate tissue changes induced by Testosterone Propionate.
68 citations
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April 2002 in “Journal of Alternative and Complementary Medicine” This study suggests that botanical 5AR inhibitors like Serenoa repens and β-sitosterol may improve symptoms of androgenetic alopecia, with 60% of treated subjects showing improvement compared to placebo.
2 citations
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January 2023 in “Uro” This study found that both a proprietary ultrahigh-pressure extract and a hexanic extract of saw palmetto showed comparable inhibition of 5α-reductase, suggesting similar potential for managing symptoms of benign prostatic hyperplasia.
October 2025 in “Scientific Reports” This study found that the extracts of Serenoa repens, when evaluated through chemical, biological, and in silico methods, demonstrated anti-inflammatory, pro-apoptotic, and anti-androgenic activities against prostate cancer cell lines, suggesting potential therapeutic benefits and directing future pharmaceutical development.