The Influence of Secoisolariciresinol Diglucoside on Non-Emasculated Rats in BPH
January 2009
in “
Journal of Jilin Medical College
”
New to Finasteride? There is a guide in the encyclopedia. Read the guide → Studysummary This study found that SDG did not significantly affect prostate weight in rats with BPH, but it may reduce serum PAP activity and alter prostate tissue changes induced by Testosterone Propionate.
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The study investigated the effects of secoisolariciresinol diglucoside (SDG) on benign prostatic hyperplasia (BPH) in non-emasculated male Wistar rats. Sixty rats were divided into six groups, with one group serving as a blank control and the others receiving various treatments, including SDG at different doses and Finasteride. All groups, except the blank control, were administered Testosterone Propionate to induce BPH. Results showed that while SDG did not significantly affect the wet weight and index of the rat prostate, it did influence serum PAP vitality and mitigated changes in prostate structure caused by Testosterone Propionate, such as thinning of the epithelium and reduced secretion. The study concluded that SDG had an inhibitory effect on BPH in rats.