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This study introduced an innovative antioxidant serum for skin care, using a lipid active from Rana catesbeiana Shaw, and validated its rejuvenating potential through physical-chemical and microbiological tests that ensured its antioxidant effectiveness, microbiological safety, and formulation stability.

In this study, prolonged ingestion of linseed in rabbits was observed to be safe, showing no significant weight gain or anatomical anomalies in liver and kidney biopsies.

This study observed that high-dose retinol palmitate was well-tolerated in resected stage I lung cancer patients, though it raised concerns about potential impacts on lipid metabolism due to elevated gamma-GT levels and triglycerides.

This study found that the imidacloprid/flumethrin collar (Seresto®) is chemically compatible with major spot-on formulations and dermally and systemically safe for adult dogs and cats when used together.

This study in Chinese patients with male pattern baldness found that 2% minoxidil solution led to moderate hair growth in 22% of participants and was generally well-tolerated.

In this study, a hair cleansing tonic using Aloe vera and red onion was developed and found effective for promoting hair growth according to sensory tests by 30 panelists in Puerto Wilches, Santander, meeting microbiological safety standards.

In this study, the authors developed a medicated face mask using electrospun fibers to deliver the active compound Eflornithine hydrochloride for managing hirsutism. The mask showed promising drug release characteristics, a high safety profile, and reduced hair growth in mice.

This study found that spironolactone therapy may reduce hair width in prepubertal girls with simple hypertrichosis, though its long-term efficacy and safety remain uncertain.

This study found that the dietary supplement RJ-SP4AGA significantly improved hair growth and reduced hair loss in post-menopausal women with androgenetic alopecia over 16 weeks.

This study developed a low-viscosity triamcinolone acetonide serum, used with a derma stamp microneedling device, to improve targeted treatment of alopecia areata, reporting favorable drug solubility, spreadability, and permeation to hair follicles, while maintaining skin safety.

This study reports that ritlecitinib, when used for up to 24 months in patients aged 12 and older with alopecia areata, has an acceptable safety profile, with a similar proportion of adverse events in both ritlecitinib and placebo groups in the placebo-controlled cohort.

This study found that proretinal nanoparticles, applied topically, are safe and effective for penetration into hair follicles, enhancing retinoid biological activity in the skin while reducing irritation compared to conventional retinal formulations.

This study found that aerosols formulated with celery extract and candlenut oil significantly stimulated hair growth in rabbits without causing skin irritation, suggesting their potential as natural and safe alternatives for treating alopecia.

This review discusses the cosmetic use and safety of Hypericum Perforatum Extract and Oil, finding that current data are insufficient to support their safety in formulations due to a lack of comprehensive testing.

The study's findings are unreliable due to retraction.

This study investigated the safety and efficacy of IV iron maltoside 1000 in treating iron-deficiency anemia among children with IBD and found a significant increase in hemoglobin levels by 6 weeks, maintained for up to a year, with minimal side effects reported.

This study observed that the addition of Cuticapil Stem Hair Serum to standard care significantly improved hair growth and reduced hair shedding in patients with androgenetic alopecia, demonstrating superior efficacy compared to standard care alone without any reported adverse events.

In this clinical trial, oral consumption of a persimmon leaf extract-containing complex significantly increased hair density and thickness over 24 weeks compared to a placebo, although improvements in hair gloss were not statistically significant.

This study reports that long-term treatment with ritlecitinib is generally well tolerated for up to approximately five years in patients aged 12 and older with alopecia areata, with the safety profile aligning with previous data from the ALLEGRO clinical trials.

This study reported that ritlecitinib was generally well tolerated over 72 months in patients aged 12 and older with alopecia areata, with adverse events like headache and nasopharyngitis observed, and safety outcomes consistent with previous studies.

In this study, the use of Dravanti beeja lepa for 28 days was observed to significantly regenerate hair in patients with Indralupta (Alopecia Areata).

Apremilast was not effective in treating moderate-to-severe alopecia areata.

This study developed an ointment from palm kernel oil and shea butter, which demonstrated improved hair growth in rabbits and may inform the creation of non-harmful hair growth products for humans.

This study found that cedrol nanoemulsions significantly promote hair follicle regeneration and reduce DHT levels in an androgenic alopecia mouse model, suggesting potential efficacy in AGA treatment.

Microfluidic models improve testing for aging, wound healing, and oral tissue, reducing animal testing.

This study used a multi-layer in silico framework to evaluate Korean herbal compounds for androgenetic alopecia, identifying Biochanin A, Saponin Re, and Emodin as potential topical candidates with distinct safety and affinity profiles, although these findings remain purely computational without experimental validation.

This study evaluated Korean herbal compounds in silico and identified Biochanin A, Saponin Re, and Emodin as potential topical treatments for androgenetic alopecia, each with specific safety and efficacy considerations.

This pilot study found that using skin patting and iontophoresis to deliver a 6% dutasteride gel led to significant improvements in hair density and shaft diameter in men and postmenopausal women with treatment-resistant androgenetic alopecia, with no reported adverse events.

This study found that human umbilical cord-derived mesenchymal stromal cell-conditioned media was safe and positively affected hair regeneration in 86.6% of participants in a pilot study.

This study found that oral finasteride is safe, well tolerated, and effective in improving hair growth in men with androgenetic alopecia, with noticeable benefits seen as early as three months into treatment.