Next-Generation In Vitro Testing: Microfluidic Models for Aging, Wound Healing, and Oral Tissue Analysis in Safety, Efficacy, and Permeation Studies

November 2024 in “ Journal of Investigative Dermatology ”

Silvia Teissier, J. Chew, Massimo Alberti

microfluidic models Skin on Chip Equivalents SoCE juvenile human fibroblasts keratinocytes epidermal thickness Lamin B1 Ki67 cytokines skin barrier function keratinocyte differentiation oral mucosa gingiva vascularized blood vessels skin chip blood flow mimicry 3D skin equivalents wound healing models oral care evaluations

Studysummary Microfluidic models improve testing for aging, wound healing, and oral tissue, reducing animal testing.

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