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This study found that a 3D wound model, the 3DWoundSE, showed improved responsiveness to injury and cytotoxic stimuli compared to an intact 3D skin equivalent, offering a reproducible and ethical alternative to animal models for early wound response assessment in dermatological research and drug development.

This study found that GelMA/HAMA bioink shows promise for 3D printing skin equivalents, as it effectively mimics the native skin's properties and supports hair follicle structure development.

This review highlights the global efforts and challenges in 3D bioprinting for developing skin substitutes, emphasizing the need for standardized protocols to enhance reproducibility and clinical applicability in wound healing and regeneration.

This study found that retinoic acid and a retinol complex formulation showed different permeation and compound localization in a skin equivalent model, with unique lipid changes observed with only the retinol formulation.

In this study, researchers developed a new 3D skin equivalent assay using mouse epidermal and dermal cells that successfully regenerated organized hair follicles, outperforming a 2D model in hair follicle orientation and quantity, and enhanced hair growth when Wnt3a was added.