research Functional Analysis of VDR Gene Mutation R343H in a Child with Vitamin D-Resistant Rickets with Alopecia
The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.
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research Physiological and Retinoid-Induced Proliferations of Epidermis Basal Keratinocytes Are Differently Controlled
Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
research Genetic Dissection of Retinoic Acid Function in Epidermis Physiology
Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.
research Stem Cells Tightly Regulate Dead Cell Clearance to Maintain Tissue Fitness
Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
research Can Antibiotic-Induced Changes in the Composition of the Hair Follicle Microbiome Regulate Human Hair Growth?
Antibiotics might affect hair growth by changing the bacteria in hair follicles.
research Complete Remission of Alopecia Areata Under Treatment of Chronic Hand Eczema with Alitretinoin
Alitretinoin may help treat alopecia areata.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor Alpha Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research Analysis of 1,25-Dihydroxyvitamin D3 Receptors in Basal Cell Carcinomas
Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.
research Retinoids Modulate MITF: A Novel Mechanism in the Regulation of Melanogenesis
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
research In Situ Detection of Retinoid-X Receptor Expression in Normal and Psoriatic Human Skin
RXR-alpha is strongly expressed in both normal and psoriatic skin and may help in skin cell differentiation and hair growth.
research Retinoid-Mediated Stimulation of Steroid Sulfatase Activity in Myeloid Leukemic Cell Lines Requires RARα and RXR and Involves the Phosphoinositide 3-Kinase and ERK-MAP Kinase Pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research An Essential Role for RXRα in the Development of Th2 Responses
RXRα is crucial for proper immune response and links diet to immune function.
research Hairless Modulates Ligand-Dependent Activation of the Vitamin D Receptor-Retinoid X Receptor Heterodimer
Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.
research Roxithromycin Antagonizes Catagen Induction in Murine and Human Hair Follicles: Implication of Topical Roxithromycin as Hair Restoration Reagent
Roxithromycin, an antibiotic, can increase hair growth and might be used as a treatment for hair loss.
research Novel Drugs Targeting Retinoic Acid Receptors
Newer retinoid drugs are effective for skin conditions but have significant side effects.
research Effect of Lithocholic Acid as a Ligand of Vitamin D Receptor on Hair Growth in Alopecia
Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.
research Vitamin D Receptor: Key Roles in Bone Mineral Pathophysiology, Molecular Mechanism of Action, and Novel Nutritional Ligands
Vitamin D and its receptor are crucial for bone health and can be influenced by certain fats and curcumin.
research Autoimmune Disease and Hair Loss
Autoimmune diseases can cause hair loss, and early treatment is important to prevent permanent damage.
research Progressive Expression of PPARGC1α Is Associated with Hair Miniaturization in Androgenetic Alopecia
Increased PPARGC1α relates to hair thinning in common baldness.
research Functional Analysis of Vitamin D Receptor Using Adenovirus Vector
The study found that certain mutations in the vitamin D receptor can cause rickets and potentially affect hair growth.
research Evidence for 1,25-Dihydroxyvitamin D3-Independent Transactivation by the Vitamin D Receptor
The vitamin D receptor can work without its usual activating molecule.
research Retinoids Modulate MITF: A Novel Mechanism in the Regulation of Melanogenesis
Retinoids can help treat skin pigmentation disorders by affecting melanin production.
research Why We Should Treat COVID-19 Long Hauler Syndromes with Convalescent Plasma; Contained Suppressive Exosomes Are Likely COVID Antigen-Specific
The document suggests using convalescent plasma to treat COVID-19 Long Hauler Syndromes because it may contain beneficial elements that target the virus.
research A Case of Simultaneous Onset of Highly Active Systemic Lupus Erythematosus and IgG4-Related Renal Disease
Renal histology is crucial for diagnosing simultaneous SLE and IgG4RD.
research Refractory Alopecia Universalis Associated with Dermatomyositis Successfully Treated with Tofacitinib
A medicine called tofacitinib worked to treat a hair loss condition linked with a muscle and skin disease.
research Hidradenitis Suppurativa Encounters in a National Electronic Health Record Database Notable for Low Dermatology Utilization, Infrequent Biologic Prescriptions, and Frequent Opiate Prescriptions
HS patients rarely see dermatologists, often get opiates, and need better care.
research Testosterone-Secreting Tumor or Insulin Resistance? Metformin as a Diagnostic and Therapeutic Trial
Metformin can help diagnose and treat high testosterone levels in women, often due to insulin resistance rather than a tumor.
research Samcyprone (Diphenylcyclopropenone Ointment) for the Treatment of Common Warts
Samcyprone ointment is effective for treating common warts if a sensitization reaction occurs first.
research Treatment of Tourette’s Syndrome With Finasteride
Finasteride may effectively reduce Tourette's syndrome symptoms and improve life quality.
research Voluntary Registers No Longer Have Gravitas
Professionals believe voluntary registers cannot ensure public safety like mandatory ones with laws.