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GlossaryBexarotene

medication used to treat certain types of skin cancer

Bexarotene is a medication primarily used to treat cutaneous T-cell lymphoma, a type of skin cancer. It works by activating retinoid X receptors, which help regulate cell growth and differentiation. While it is not specifically used for hair loss or alopecia, its effects on cell growth have been studied in various contexts, including dermatological conditions.

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research Phase I/II Randomized Bilateral Half-Head Comparison of Topical Bexarotene 1% Gel for Alopecia Areata

44 citations, October 2009 in “Journal of the American Academy of Dermatology”

Topical bexarotene 1% gel might help regrow hair in alopecia areata and is generally safe.

research Bexarotene Gel: A New Topical Therapy for Alopecia Areata

4 citations, January 2010 in “International journal of trichology”

Bexarotene gel shows promise as a new treatment for alopecia areata.

research Results of Stage I in a Phase II Randomized Bilateral Comparison of Bexarotene 1% Topical Gel in Alopecia Areata

March 2005 in “Journal of the American Academy of Dermatology”

Bexarotene 1% topical gel helped some patients with alopecia areata regrow hair.

research The Spectrum of Hair Loss in Patients with Mycosis Fungoides and Sézary Syndrome

39 citations, October 2010 in “Journal of The American Academy of Dermatology”

Some patients with mycosis fungoides or Sézary syndrome experience hair loss, which may be similar to alopecia areata or linked to skin lesions, possibly due to abnormal T cells, and bexarotene can help treat it.

research Follicular Mycosis Fungoides: Variability of a Rare Entity

8 citations, January 2005 in “SKINmed Dermatology for the Clinician”

FMF and mycosis fungoides are variants of the same disease, and bexarotene can be an effective treatment.

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