An Essential Role for RXRα in the Development of Th2 Responses

    December 2005 in “ European Journal of Immunology ”
    Xin Du, Koichi Tabeta, Navjiwan Mann … Bruce Beutler
    Studysummary This study found that a specific mutation in the mouse RXRalpha gene significantly impacts immune responses and causes hair loss and skin cysts.
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    Research cited in this study 2

    1. Skin Abnormalities Generated by Temporally Controlled RXRα Mutations in Mouse Epidermis Nature · 2000
    2. The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed Journal of bone and mineral research · 1998