Refractory Alopecia Universalis Associated with Dermatomyositis Successfully Treated with Tofacitinib

March 2022 in “ Modern Rheumatology Case Reports ”

Rochelle Castillo, Jemima Albayda

alopecia universalis dermatomyositis tofacitinib Xeljanz

TLDR A medicine called tofacitinib worked to treat a hair loss condition linked with a muscle and skin disease.

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4 / 4 results

research An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis

130 citations , July 2018 in “Journal of Investigative Dermatology”

Tofacitinib may help treat severe hair loss, but more research is needed.

research Oral Ruxolitinib Induces Hair Regrowth in Patients with Moderate-to-Severe Alopecia Areata

196 citations , September 2016 in “JCI insight”

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

research Safety and Efficacy of the JAK Inhibitor Tofacitinib Citrate in Patients with Alopecia Areata

222 citations , September 2016 in “JCI insight”

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

research Type 1 Interferon Signature in the Scalp Lesions of Alopecia Areata

52 citations , March 2010 in “British Journal of Dermatology”

Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.

8 / 8 results

research Efficacy of Janus Kinase Inhibitors in Adult Patients With Alopecia Areata

August 2023 in “International journal of research in dermatology”

Janus kinase inhibitors are effective and generally safe for treating hair loss in adults with alopecia areata.

$Refractory Alopecia Universalis Associated with Dermatomyositis Successfully Treated with Tofacitinib$

research Refractory Alopecia Universalis Associated with Dermatomyositis Successfully Treated with Tofacitinib

2 citations , March 2022 in “Modern Rheumatology Case Reports”

A medicine called tofacitinib worked to treat a hair loss condition linked with a muscle and skin disease.

research Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib

4 citations , July 2018 in “PubMed”

Oral and topical tofacitinib can help regrow hair in people with severe alopecia areata.

research An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis

130 citations , July 2018 in “Journal of Investigative Dermatology”

Tofacitinib may help treat severe hair loss, but more research is needed.

research Alopecia Universalis Unresponsive to Treatment with Tofacitinib: Report of a Case with a Brief Review of the Literature

8 citations , January 2017 in “Dermatology online journal”

Tofacitinib helped psoriasis but not alopecia universalis, needing more research.

$Successful Treatment of Refractory Alopecia Areata Universalis and Psoriatic Arthritis, But Not Plaque Psoriasis with Tofacitinib in a Young Woman$

research Successful Treatment of Refractory Alopecia Areata Universalis and Psoriatic Arthritis, But Not Plaque Psoriasis with Tofacitinib in a Young Woman

24 citations , January 2017 in “Acta dermato-venereologica”

Tofacitinib helped a young woman's severe hair loss and arthritis but not her plaque psoriasis.

research Efficacy of Tofacitinib in Treatment of Alopecia Universalis in Two Patients

51 citations , June 2016 in “Journal of the European Academy of Dermatology and Venereology”

Tofacitinib was effective in treating hair loss in two patients with alopecia universalis.

research Transient Efficacy of Tofacitinib in Alopecia Areata Universalis

39 citations , April 2016 in “Case Reports in Dermatology”

Tofacitinib temporarily regrew hair in a man with alopecia, but its effects didn't last.