research 1049 Novel strategy to promote hair follicle growth and stem cell activation in human male scalp skin: Targeting prolactin receptor with ABS-201
ABS-201 may effectively promote hair growth in men by targeting the prolactin receptor.
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90-120 / 1000+ resultsresearch 75993 Safety of Janus kinase inhibitors for treatment of alopecia areata
JAK inhibitors are generally safe for treating alopecia areata.
research 75478 Symptoms, Emotional and Functional Impacts by Hair Loss Severity in Alopecia Areata
research 73192 Consistent Efficacy of Upadacitinib in Alopecia Areata Subgroups: Adult, Pediatric, Severe Disease, and JAK-Refractory Patients — A Meta-Analysis
research 75122 Real-world Effectiveness of Baricitinib for Severe Alopecia Areata by Baseline Hair Loss and Episode Duration: Results from a Prospective Observational Study
Baricitinib helps regrow hair in severe alopecia areata, with results varying by initial hair loss severity and episode duration.
research 73571 The real-world impact of JAK inhibitor treatment on anxiety and depression outcomes and the role of eyebrow and eyelash hair regrowth in alopecia areata: TARGET-DERM
JAK inhibitors help regrow eyebrow and eyelash hair and improve anxiety and depression in some alopecia areata patients.
research Efficacy and safety of twice-weekly and thrice-weekly dutasteride compared to finasteride in men with androgenetic alopecia: A randomized, investigator-blind, active-controlled, parallel-group pilot study
In this study, twice-weekly and thrice-weekly dutasteride improved hair growth and were well-tolerated, although thrice-weekly dosing did not significantly outperform finasteride 1 mg daily for increasing hair count.
research Oral Minoxidil 2.5mg vs 5mg for Male Androgenetic Alopecia: A Double-Blind Randomized Clinical Trial.
Both 2.5 mg and 5 mg doses of oral minoxidil are effective for hair regrowth in men with hair loss.
research 62045 Dermatologist Utilization of Medications Associated with Androgenic Alopecia Treatment Among Medicare Beneficiaries
research 63748 Combined Regenerative Technique: A New Therapeutical Option for Androgenetic Alopecia
research 64082 Combined Minoxidil and Platelet-Rich Plasma Compared With Monotherapy in Androgenetic Alopecia: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Combining minoxidil and PRP is more effective for hair growth than using either alone.
research Use of oral minoxidil for androgenetic alopecia in transgender and gender-diverse people. A retrospective study of 27 patients.
Oral minoxidil can effectively treat hair loss in transgender and gender-diverse individuals.
research Real‐life effectiveness and safety of baricitinib in patients with severe alopecia areata: A 24‐week Italian study
This study found that baricitinib significantly reduced hair loss in patients with severe alopecia areata, decreasing the mean SALT score from 96.6 to 48 over 24 weeks, with no patients dropping out and only mild adverse events in 12.7% of participants.
research Deep Hair Phenomics: Implications in Endocrinology, Development, and Aging
This study developed a deep learning-based tool to quantify individual hair fibers in mice, revealing distinct hair phenotypes linked to hormonal, genetic, and age-related factors, and suggesting its potential for new diagnostic methods through hair analysis.
research 51252 Oral supplementation with L-Cystine, Serenoa repens, Pumpkin seed oil and Pygeum africanum in Chronic Telogen Effluvium and Androgenetic Alopecia: A double-blind, placebo-controlled, randomized clinical study
No specific results were reported in this abstract; it aims to explore the psychological effects of hair loss conditions like Chronic Telogen Effluvium and Androgenetic Alopecia, emphasizing the potential link between micronutrient deficiency and hair health.
research 51297 Low dose oral minoxidil in COVID-19-associated telogen effluvium. A retrospective analysis of 69 patients.
This study addresses the scarcity of information on the effectiveness and safety of low-dose oral minoxidil for treating COVID-19-associated telogen effluvium, a type of hair loss observed in some patients after COVID-19 infection, but does not report specific results.
research 53039 The prevalence of androgenetic alopecia with hormone therapy in transgender men: a systematic review and single-arm meta-analysis
This study aims to evaluate the prevalence of androgenetic alopecia in transgender men undergoing testosterone therapy, noting that such hormone treatment can lead to dermatological issues that significantly affect their quality of life. Results are not reported in the abstract.
research 51826 PRO-C22 - A Novel Serological Biomarker of Tissue Damage is Associated with Disease Severity, Disease Activity, and Systemic Inflammation in Patients with Hidradenitis Suppurativa
PRO-C22 can help diagnose and monitor the severity of hidradenitis suppurativa.
research Adipose tissue remodeling via TSLP-mediated IL-4/IL-13 signaling: Implications for atopic dermatitis and skin barrier
In this study, thymic stromal lymphopoietin (TSLP) induced IL-4/IL-13 from T cells, prompting sebum secretion and adipose loss, suggesting IL-4/IL-13 may affect skin barrier function in atopic dermatitis.
research A 15-YEAR-OLD FEMALE PATIENT DIAGNOSED WITH SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) AND INITIALLY PRESENTED WITH LUPUS NEPHRITIS, CEREBRITIS, AND DIFFUSE ALVEOLAR HEMORRHAGE (DAH)
This case report illustrates that diffuse alveolar hemorrhage can be a serious initial manifestation of systemic lupus erythematosus, characterized by progressive dyspnea, hemoglobin decrease, and respiratory symptoms.
research This month in JAAD Case Reports: October 2023—Central centrifugal cicatricial alopecia in Black men
CCCA affects Black men too, with a genetic link found in the PADI3 gene.
research Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation
In this study, researchers found that Dlx3 plays a crucial role in regulating chromatin accessibility and gene transcription during keratinocyte differentiation in the epidermis, highlighting its potential impact on epidermal barrier formation and differentiation.
research This Month in JAAD Case Reports: August 2022
This systematic review reported objective clinical improvement with low-dose oral minoxidil in up to 100% of patients with androgenetic alopecia and up to 82.4% with alopecia areata.
research 917 Frontal fibrosing alopecia scalp profiling links Th1/Th2 and JAK3 activation with fibrosis and loss of follicular stem cells
Targeting immune pathways like JAK/STAT may help treat frontal fibrosing alopecia.
research 513 Demonstration of hair health benefits using an oral supplement
This study found that women taking a daily oral supplement with omega-3 fatty acids, phytonutrients, and antioxidants for 14 weeks reported perceived improvements in hair growth, strength, and moisturization.
research 666 Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in follicular dystrophy and primary cicatricial alopecia
Mutations in Far2 mice cause hair loss due to sebaceous gland issues.
research 132 Design of an in vitro skin 3D model mimicking a disruption of the barrier function
This study suggests that activating the hexosamine pathway may enhance skin homeostasis, potentially increasing hair follicle stem cells and modifying extracellular matrix components like hyaluronic acid in vitro.
research 254 WITHDRAWN
In this study, the novel ASAXA-μCT imaging method identified that the shrinkage of sweat glands with aging causes dermal defects, reducing skin elasticity and contributing to wrinkling and sagging.
research 845 Dermal lymphatic vessels promote hair follicle growth via the BMP inhibitor Sostdc1
This study found that lymphatic vessels promote hair follicle growth in mice, suggesting new therapeutic strategies for hair loss treatments.
research CME examination
Control symptoms and use safe treatments for skin conditions like lichen planopilaris and chronic cutaneous lupus erythematosus.