August 2016 in “Journal of Investigative Dermatology” Activating Nrf2 can improve wound healing by increasing hair follicle stem cells.
May 2015 in “Journal of The American Academy of Dermatology” This study found that oral minoxidil 5 mg daily significantly improved hair growth in men with androgenetic alopecia, though it may cause minor side effects like hypertrichosis and pedal edema.
September 2012 in “African Journal of Urology” This review describes the clinical features of testosterone deficiency syndrome in aging men but reports no new experimental findings, highlighting the need for clinical recognition and treatment of TDS.
March 2012 in “Journal of Pediatric and Adolescent Gynecology” This study found significant variability among NASPAG members in diagnostic approaches for PCOS, though there was more agreement on recommended first-line therapies such as oral contraceptives and lifestyle changes.
666 citations
,
September 1977 in “British Journal of Dermatology” This article presents a classification system for stages of female-pattern androgenetic alopecia to aid early diagnosis and mentions existing systems for rare male-pattern cases, but reports no new clinical results.
467 citations
,
October 2014 in “European Journal of Endocrinology” This paper reviews the diagnostic criteria, etiological factors, and treatment approaches for PCOS, highlighting the importance of considering metabolic issues such as insulin resistance and obesity, but reports no new findings.
419 citations
,
January 2015 in “Journal of Consumer Research” This study found that corporate social responsibility can enhance consumer perceptions of product performance, especially when viewed as motivated by genuine benevolence rather than self-interest.
397 citations
,
February 2004 in “British Journal of Dermatology” This article reviews the mechanisms by which minoxidil stimulates hair growth and reports no new clinical findings.
385 citations
,
November 1990 in “Journal of Cell Science” This study successfully grew and maintained human hair follicles in vitro, noting that TGF-β1 negatively affects growth, while EGF replicates hair-removal effects seen in animals.
281 citations
,
January 2013 in “British Journal of Dermatology” Manage vitiligo with treatments, address emotions, and use camouflage techniques.
255 citations
,
October 1985 in “The Journal of Clinical Endocrinology & Metabolism” This study concluded that albumin-bound testosterone is biologically important and significantly contributes to testosterone bioavailability in women receiving spironolactone.
239 citations
,
July 2002 in “Clinical and Experimental Dermatology” This review explores the role of nutritional factors in hair loss, noting that iron and l-lysine supplementation may benefit some individuals, while excessive supplements can lead to hair shedding.
234 citations
,
February 2001 in “British Journal of Dermatology” FPHL affects hair density and diameter, causing visible hair loss in older women.
218 citations
,
April 2012 in “British Journal of Dermatology” This updated guideline from the British Association of Dermatologists discusses current recommendations for managing alopecia areata but reports no new clinical research findings.
216 citations
,
June 2015 in “PLANT PHYSIOLOGY” This study found that OsPHR3 overexpression in rice led to significant tolerance to low-phosphorus stress and normal growth under normal conditions, suggesting its potential for improving phosphorus uptake efficiency.
205 citations
,
April 2013 in “British Journal of Dermatology” In this study, platelet-rich plasma significantly increased hair regrowth and reduced symptoms of alopecia areata compared to triamcinolone acetonide or placebo, with no observed side effects.
200 citations
,
October 2009 in “European journal of endocrinology” This review discusses the multifaceted actions of metformin in polycystic ovary syndrome and reports no new clinical results; the authors emphasize metformin's potential benefits in both cardiometabolic and reproductive aspects of PCOS.
193 citations
,
August 1985 in “Endocrinology” This study found significant species differences in the enzyme activity and inhibitor affinities of prostatic 5α-reductases from rats, dogs, and humans, with variable potencies for different 3-oxo-4-azasteroid inhibitors across species.
192 citations
,
March 1998 in “British Journal of Dermatology” This study found that minoxidil significantly increases VEGF mRNA and protein expression in dermal papilla cells, suggesting a role in enhancing hair follicle vascularization in androgenetic alopecia.
191 citations
,
May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” This study reviewed recent theories on alopecia areata's pathogenesis, highlighting its autoimmune nature due to immune privilege disruption in hair follicles, and noted current treatments have limited efficacy with high relapse rates, underscoring the need for further research into its mechanisms for better therapies.
187 citations
,
May 1979 in “British Journal of Dermatology” In this report, six elderly women with a novel pustular dermatosis of the scalp experienced chronic lesions unresponsive to antibiotics but were effectively managed with potent topical steroids.
180 citations
,
September 1999 in “British Journal of Dermatology” This review discusses the psychological and social impacts of androgenetic alopecia and suggests that medical treatments can have some positive psychological effects, highlighting the condition's moderate stress and impact on body image.
179 citations
,
March 2005 in “British Journal of Dermatology” This study found that 88% of women with female pattern hair loss who received oral antiandrogens saw no progression or improvement in their condition.
177 citations
,
July 2004 in “The Journal of Sexual Medicine” This review provides updated guidelines for diagnosing and managing women's sexual dysfunctions but reports no new clinical findings; it emphasizes the need for ongoing research and long-term outcome studies.
177 citations
,
November 2002 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, stable types of leucoderma such as segmental vitiligo and piebaldism showed 100% repigmentation after melanocyte transplantation, suggesting surgery as the preferred method for these conditions.
173 citations
,
July 2012 in “British Journal of Dermatology” This study found that the administration of the mutant BRAF inhibitor dabrafenib in patients with metastatic melanoma was associated with various skin lesions, including keratinocytic proliferation that sometimes showed low-grade malignancy features.
169 citations
,
September 2002 in “British journal of dermatology/British journal of dermatology, Supplement” This study reports that ZD1839 (Iressa), an anticancer drug, was associated with acneiform eruptions and hair growth abnormalities due to its inhibition of epidermal growth factor receptor signaling in the skin.
159 citations
,
August 2010 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, hydroxychloroquine significantly reduced signs and symptoms of frontal fibrosing alopecia after 6 months of treatment, with maximal benefits observed within the first 6 months.
157 citations
,
July 2001 in “British Journal of Dermatology” In this study, the prevalence of androgenetic alopecia among Korean men and women was found to be lower than in caucasians, with Korean men showing more frontal hairline preservation and a higher incidence of 'female pattern' hair thinning.
155 citations
,
September 2008 in “British journal of dermatology/British journal of dermatology, Supplement” This study observed that frontal fibrosing alopecia predominantly affects postmenopausal women, can be associated with lichen planus, and may lead to progressive hairline recession, though this progression is not consistent in all cases.