The Prevalence of Androgenetic Alopecia with Hormone Therapy in Transgender Men: A Systematic Review and Single-Arm Meta-Analysis

September 2024 in “ Journal of the American Academy of Dermatology ”

Marcos R. G. de Freitas, Melissa Burla, Larissa Hespanhol, Caroline Cristine Almeida Balieiro, Sabrina Wantowski, Patrícia Coutinho, Pablo Silva, Lilia Maria Lima de Oliveira

androgenetic alopecia testosterone therapy hormone therapy transgender men dermatological monitoring AAG

TLDR Many transgender men on testosterone therapy experience hair loss.

This systematic review and meta-analysis evaluated the prevalence of androgenetic alopecia (AAG) in transgender men undergoing testosterone therapy. By analyzing data from seven studies with a total of 1,624 patients, the study found that 92 patients developed AAG, resulting in a pooled prevalence of 12.54% (95% CI 2.87% to 41.02%; p<0.01; I2=96%). The findings indicate a significant occurrence of AAG in transgender men receiving hormone therapy, aligning with previous literature on the subject.

View this study on secure.jbs.elsevierhealth.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

in Progress Pictures 224 upvotes 8 months ago

A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

community Taking Charge of Your Hair: The "Big 3 Stack" Explained for 2023

in Research/Science 129 upvotes 1 year ago

The "Big 3 Stack" for hair loss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hair loss causing hormones. Microneedling can boost Minoxidil's effects.

community Why is it that low testosterone causes hair loss as well? How can I be balding?

in Chat 158 upvotes 8 months ago

The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 8 months ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community Found the solution tressbros - 1.5 years 2.5mg oral minox, 5mg finasteride, 8mg estradiol valerate (weekly)

in Transgender 591 upvotes 10 months ago

The conversation discusses a transgender individual's successful hair loss treatment over 1.5 years using 2.5mg oral minoxidil, 5mg finasteride, and 8mg weekly injectable estradiol valerate. Some users debate the appropriateness of this approach within the group's goals, while others support the individualized treatment and its additional benefits for transgender individuals.

community Estrogen is an anabolic for scalp hair, if you mix it with growth stimulants such as oral minoxidil. All we need is an artificial SARM-estrogen that will work only with hair and will be invisible for the rest of the body + some next level AA only for hair – goodbye hair transplant industry

in Transgender 137 upvotes 3 years ago

Hair loss discussion mentions using estrogen mixed with growth stimulants like oral minoxidil for scalp hair growth. Idea proposed for an artificial SARM-estrogen that only affects hair without body side effects.

Similar Research

5 / 1000+ results

research Endocrinology of Transgender Medicine

166 citations, October 2018 in “Endocrine Reviews”

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Medical Dermatologic Conditions in Transgender Women

The Prevalence of Androgenetic Alopecia with Hormone Therapy in Transgender Men: A Systematic Review and Single-Arm Meta-Analysis

Related Community Posts Join

community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

community Taking Charge of Your Hair: The "Big 3 Stack" Explained for 2023

community Why is it that low testosterone causes hair loss as well? How can I be balding?

community Quit vaping/smoking = 80% less loss

community Found the solution tressbros - 1.5 years 2.5mg oral minox, 5mg finasteride, 8mg estradiol valerate (weekly)

Similar Research

research Endocrinology of Transgender Medicine

research Medical Dermatologic Conditions in Transgender Women

research Dermatological Considerations for Transgender and Gender Diverse Patients: An Australian Perspective

research Characterizing Dermatological Conditions in the Transgender Population: A Cross-Sectional Study

research Use of High-Dose Cyproterone Acetate and Risk of Intracranial Meningioma in Women: Cohort Study