research The Paradox of p53: What, How, and Why?
The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
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research Modulation of Glucocorticoid Action and the Treatment of Type-2 Diabetes
Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
research Male Androgenetic Alopecia
DHT, a testosterone byproduct, causes male pattern baldness.
research Chitosan Microparticles for Sustaining the Topical Delivery of Minoxidil Sulphate
Chitosan microparticles improve minoxidil sulphate delivery, potentially reducing daily applications.
research Steroidogenic Isoenzymes in Human Hair and Their Potential Role in Androgenetic Alopecia
Steroidogenic isoenzymes may help improve treatments for common hair loss.
research Topical Application of Ketoconazole Stimulates Hair Growth in C3H/HeN Mice
Putting ketoconazole on the skin can help mice grow hair.
research Synthesis and Biological Evaluation of Amino-Pyridines as Androgen Receptor Antagonists for Stimulating Hair Growth and Reducing Sebum Production
A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.
research Vitamin D Activates Type A Natriuretic Peptide Receptor Gene Transcription in Inner Medullary Collecting Duct Cells
Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.
research Worth a Second Look: A 72-Year-Old Man with Significant Fatigue and Weight Loss
A 72-year-old man had severe fatigue, weight loss, and frequent loose stools.
research Diphenyl Ethers as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.
research Medication Repurposing: New Uses for Old Drugs
Old drugs can be used for new treatments, saving time and money, but there are challenges like needing more evidence and legal concerns.
research Pantolactams as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
research Copper Deficiency: A New Reason for Androgenetic Alopecia?
Copper deficiency may cause hair loss, and treating it could involve nutrition and hormones.
research 5α-Reductase Inhibitors: The Finasteride Story
Finasteride safely treats enlarged prostate and male-pattern baldness.
research RGB Video Microscopic System for In Vitro Monitoring of Optical Properties of Hair Shaft and Follicle
The system helps monitor hair properties using RGB video microscopy.
research Assessing Auditory and Cochlear Function in Alopecia Areata Patients: Exploring the Link to Cochlear Melanocyte Damage
Alopecia areata may be linked to hearing problems, so patients should monitor their hearing.
research Anthocyanin as Colorectal Anticancer: A Brief Review
Anthocyanins from fruits and vegetables may help prevent and treat colorectal cancer safely.
research The First Visit: Consultation and Workup Before Sperm Banking
A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.
research Follicular Transport Route: Research Progress and Future Perspectives
Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.
research Genome-Wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage
Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.
research Transfollicular Drug Delivery: Is It a Reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.
research Follicular Targeting: A Promising Tool in Selective Dermatotherapy
Targeting hair follicles can improve skin treatments and reduce side effects.
research MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway
MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
research Treatments for Androgenetic Alopecia and Alopecia Areata
Minoxidil and finasteride treat hair loss; more research needed for other options.
research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research Cyclic Dynamics of Hair Follicles and the Effect of Minoxidil on the Bald Scalps of Stumptailed Macaques
Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.
research Types of Hair Loss and Treatment Options, Including the Novel Low-Level Light Therapy and Its Proposed Mechanism
Hair loss treatments include medications and new methods like low-level light therapy, which may work by boosting cell activity and blood flow.
research Therapeutic Strategies for Treating Hair Loss
The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
research Androgenetic Alopecia: In Vivo Models
Stump-tailed macaque best for researching hair loss causes and treatments.
research Validated HPTLC Method for the Simultaneous Determination of Alfuzosin, Terazosin, Prazosin, Doxazosin, and Finasteride in Pharmaceutical Formulations
Method can accurately measure five BPH drugs at once.